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Efficacy and Tolerance of Antipsychotics Used for the Treatment of Patients Newly Diagnosed with Schizophrenia: A Systematic Review and Meta-Analysis.

Author: BallPatrick Anthony, MorrisseyHana, Sherzad QadirZina

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Aripiprazole showed better individual patient response and tolerability than other oral antipsychotics like ziprasidone and quetiapine. Quetiapine was better tolerated than aripiprazole, ziprasidone, and risperidone. Ziprasidone had better tolerability than quetiapine, haloperidol, and olanzapine. The study emphasizes that individual patient response, tolerability, and life-threatening side effects should be considered when choosing antipsychotics.
Paper Details　
Original Abstract of the Article :
This systematic review compared the efficacy and tolerance of oral antipsychotics (APDs) used in the treatment of schizophrenia following the PRISMA-P&#169; statement (<i>n</i> = 21). The primary outcomes of interest were clinical response measured with symptoms' improvement, tolerance to side effec...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661248/

データ提供：米国国立医学図書館（NLM）

Antipsychotics for Schizophrenia: A Journey Through the Desert of Treatment Options

Schizophrenia, a complex mental illness, presents a challenging desert to navigate, with researchers constantly searching for effective treatments. This systematic review compares the efficacy and tolerance of various oral antipsychotics (APDs) used in the treatment of schizophrenia, offering a comprehensive guide to clinicians navigating this complex landscape. The authors systematically analyze a wide range of studies, seeking to understand the relative effectiveness and side effects of different APDs.

The Hidden Oases of Treatment Effectiveness

The review reveals variations in treatment effectiveness and tolerability among different APDs, offering valuable guidance for clinicians. Aripiprazole emerged as a potentially more effective and well-tolerated option compared to other APDs, suggesting its potential as a preferred treatment. This research, like a desert explorer discovering valuable resources, helps identify the most promising treatments, paving the way for improved patient outcomes.

Navigating the Desert of Treatment Choices: A Personalized Approach

This study emphasizes the importance of a personalized approach to treatment, considering individual patient characteristics and responses. The authors highlight that treatment decisions should be based on individual patient needs and preferences, ensuring the best possible outcomes. Just as a desert traveler adapts their journey to the specific conditions, clinicians must tailor their treatment plans to individual patients.

Dr.Camel's Conclusion

This systematic review provides valuable insights into the effectiveness and tolerability of different antipsychotics used in the treatment of schizophrenia. It offers a comprehensive guide to clinicians navigating this complex desert, helping them identify the most appropriate treatments for their patients. Like a desert traveler equipped with a reliable map, clinicians can utilize this information to make informed decisions, ensuring the best possible care for those living with schizophrenia.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-23
Further Info :

Pubmed ID

37987385

DOI: Digital Object Identifier

PMC10661248

Related Literature

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・Side Effects of quetiapine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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