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Impact of compliance to oral cysteamine treatment on the costs of Kidney failure in patients with nephropathic cystinosis in the United Kingdom.

Author: AzimpourKhashayar, CarlotSara, GameDavid, LashilolaSeun, McCarthyMichael, XuWeiwei, van der VoortJudith

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Nephropathic Cystinosis (NC) is a rare disease causing progressive kidney failure (KF), requiring lifelong cysteamine therapy. This study examines the impact of compliance on the lifetime costs of treating KF in NC patients in the United Kingdom, considering the often-compromised adherence to cysteamine treatment.
Paper Details　
Original Abstract of the Article :
Nephropathic Cystinosis (NC), a rare disease characterised by intra-lysosomal accumulation of cystine, results in progressive kidney failure (KF). Compliance to lifelong oral cysteamine, the only therapy, is often compromised. The relationship between compliance and costs of NC has not been previous...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688492/

データ提供：米国国立医学図書館（NLM）

The Impact of Compliance on the Cost of Cystinosis Treatment

Nephropathic cystinosis (NC) is a rare genetic disorder that causes the accumulation of cystine in cells, leading to progressive kidney failure. This study examines the relationship between compliance to oral cysteamine treatment, the only available therapy for NC, and the cost of kidney failure treatment in the United Kingdom.

The researchers developed a model to evaluate the impact of compliance on lifetime direct costs of treating kidney failure in NC patients. They found that poor compliance to cysteamine treatment significantly increased the cost of managing kidney failure, highlighting the importance of adherence to therapy for managing this debilitating disease.

Improving Patient Adherence to Treatment

This study emphasizes the need for strategies to improve patient adherence to cysteamine treatment, potentially leading to better health outcomes and reduced healthcare costs.

The Importance of Patient Education and Support

The study highlights the importance of patient education and support programs to encourage adherence to treatment and improve the management of NC.

Dr.Camel's Conclusion

The journey of managing NC is a long and challenging one, requiring patients to navigate the desert of treatment adherence. This study reminds us that even with effective therapies, achieving optimal health outcomes hinges on consistent compliance. It underscores the importance of providing patients with the knowledge, support, and resources they need to adhere to their treatment plans and ultimately achieve a better quality of life.

Date :
  1. Date Completed 2023-12-01
  2. Date Revised 2023-12-01
Further Info :

Pubmed ID

38031005

DOI: Digital Object Identifier

PMC10688492

Related Literature

Article Analysis
・Effective treatment of kidney failure
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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