Paper Details 
Original Abstract of the Article :
A woman in her 60s was admitted for refractory thrombocytopenia, initially presumed to be from immune thrombocytopenia (ITP). She was treated with the thrombopoietin receptor agonist (TPO-RA) avatrombopag, as well as prophylactic ciprofloxacin and fluconazole for neutropenia. She developed an anion ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10711905/

データ提供:米国国立医学図書館(NLM)

Avatrombopag and Lactic Acidosis: Uncovering a Potential Side Effect

This study explores the potential side effects of avatrombopag, a medication used to treat thrombocytopenia. The researchers investigated a case report of a patient who developed lactic acidosis, a potentially serious condition characterized by an accumulation of lactic acid in the blood, after receiving avatrombopag therapy.

The researchers meticulously ruled out other potential causes of lactic acidosis, ultimately attributing the condition to avatrombopag. They observed a dose-dependent relationship between avatrombopag administration and lactic acidosis development, suggesting that higher doses of the medication may increase the risk of this side effect. The study emphasizes the importance of monitoring patients receiving avatrombopag for potential complications, including lactic acidosis, and adjusting treatment regimens accordingly.

Avatrombopag: Benefits and Risks

The study's findings highlight the importance of balancing the benefits and risks of avatrombopag therapy. While this medication can be effective in treating thrombocytopenia, it can also cause serious side effects, including lactic acidosis. The study's findings provide valuable information for healthcare professionals in making informed decisions about avatrombopag use and managing potential complications.

Navigating the Complexities of Medication Side Effects

The study underscores the importance of ongoing vigilance in monitoring for potential medication side effects. The researchers' meticulous investigation of the patient's condition, ruling out other potential causes of lactic acidosis, is crucial in understanding the complex interplay between medications and adverse events. The study serves as a reminder that even seemingly safe medications can have unexpected side effects, emphasizing the need for careful observation and prompt intervention when necessary.

Dr.Camel's Conclusion

Just as a vast desert can hold hidden dangers beneath its shimmering surface, the world of medication can also harbor unexpected side effects. This study is a reminder that even seemingly safe medications can have complex interactions with our bodies. The researchers' thorough investigation and emphasis on dose-dependent effects highlight the importance of vigilant monitoring and informed decision-making in managing potential complications. By embracing a cautious approach, we can help ensure that patients receive the optimal benefits of medication therapy while minimizing potential risks.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-12-07
Further Info :

Pubmed ID

38061849

DOI: Digital Object Identifier

PMC10711905

Related Literature

SNS
PICO Info
in preparation
Languages

English

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