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A trial of tiaramide in asthma.

Author: HarveyJ E, JonesP, TanserA R

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Tiaramide is a useful oral therapy in asthma, particularly for patients intolerant of oral beta-adrenergic agonists. It is more effective than placebo and has fewer side effects than salbutamol.
Paper Details　
Original Abstract of the Article :
Tiaramide hydrochloride is a new non-steroidal anti-inflammatory agent previously shown to inhibit allergic responses both in vitro and in vivo. Clinical studies in asthmatic adults and children have also shown benefit. We report a double blind cross-over study in 35 adult asthmatic patients compari...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1111/j.1398-9995.1985.tb00216.x

データ提供：米国国立医学図書館（NLM）

Tiaramide: A New Oasis in the Desert of Asthma Treatments

The quest for [effective asthma treatments] is ongoing, and this study explores the [potential of tiaramide] as a [non-steroidal anti-inflammatory agent] for [asthma management]. The authors conducted a [double-blind, crossover study] to compare the [effectiveness] of [tiaramide] with [salbutamol] and [placebo] in [adult asthmatic patients]. It's like a camel caravan venturing into a new territory, seeking a solution to a pressing problem.

Tiaramide: A Promising Alternative for Asthma Treatment

The study found that [tiaramide] and [salbutamol] were [significantly more effective] than [placebo] in [reducing asthma symptoms] and [improving lung function]. It’s like finding a refreshing oasis in the desert, offering a new source of relief. Moreover, [tiaramide] was [better tolerated] than [salbutamol], with [fewer side effects] reported by patients. These findings suggest that [tiaramide] could be a [valuable treatment option] for [patients with asthma], particularly those who are [intolerant of oral beta-adrenergic agonists].

A New Path: Seeking Better Asthma Treatments

This study offers a promising new path for [managing asthma]. It’s like discovering a new route across the desert, leading to a healthier future for patients. The research highlights the potential of [tiaramide] as a [safe and effective] alternative to [traditional asthma treatments]. This finding could significantly impact the way [asthma] is managed in the future.

Dr.Camel's Conclusion

This research suggests that tiaramide is a promising non-steroidal anti-inflammatory agent for the treatment of asthma. It’s like finding a new oasis in the desert of asthma medications. The study's findings suggest that tiaramide is a safe, effective, and well-tolerated treatment option, particularly for patients who are intolerant of oral beta-adrenergic agonists. This development could offer new hope for a more comfortable and manageable life for individuals with asthma.

Date :
  1. Date Completed 1985-05-29
  2. Date Revised 2019-08-20
Further Info :

Pubmed ID

3887976

DOI: Digital Object Identifier

10.1111/j.1398-9995.1985.tb00216.x

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PICO Info
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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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