Paper Details

  1. Home
  2. Paper Details

Bethanidine sulfate: efficacy in prevention of ventricular tachyarrhythmias during programmed stimulation. Report of a multicenter study of 56 patients.

Author: FisherJ D, KimS G, MatosJ A, TeichmanS L, WaspeL E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Bethanidine sulfate was not effective in preventing ventricular tachyarrhythmias in 56 patients. Hypotension was a common side effect.
Paper Details　
Original Abstract of the Article :
Twelve cardiac electrophysiology centers conducted an open label prospective trial of bethanidine sulfate, an oral bretylium analog, for the prevention of ventricular tachyarrhythmias during programmed electrical stimulation. The study group included 56 patients (44 men, 12 women; mean age 60 years;...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/s0735-1097(85)80106-6

データ提供：米国国立医学図書館（NLM）

Bethanidine Sulfate: A Limited Efficacy in Preventing Ventricular Tachyarrhythmias

Ventricular tachyarrhythmias are like a desert storm in the heart, causing erratic heartbeats that can be life-threatening. This study explores the efficacy of Bethanidine sulfate, an oral bretylium analog, in preventing these arrhythmias during programmed electrical stimulation. The researchers conducted a multicenter trial to evaluate the effectiveness of this drug in a large group of patients.

Bethanidine Sulfate: Limited Success in Preventing Ventricular Tachyarrhythmias

While Bethanidine sulfate showed some potential, the study found that its efficacy in preventing ventricular tachyarrhythmias during programmed electrical stimulation was limited. The drug did not prevent arrhythmias in a significant number of patients, and side effects such as hypotension were common.

Navigating the Desert of Heart Arrhythmias

This study emphasizes the importance of ongoing research and development of new treatments for ventricular tachyarrhythmias. While Bethanidine sulfate showed some promise, further research is needed to find more effective therapies. It's like navigating a vast desert, where finding a reliable source of water is essential for survival.

Dr.Camel's Conclusion

The study on Bethanidine sulfate for the prevention of ventricular tachyarrhythmias found that the drug's efficacy was limited. The results highlight the ongoing need for research and development of new and effective treatments for heart arrhythmias.

Date :
  1. Date Completed 1985-10-04
  2. Date Revised 2019-07-08
Further Info :

Pubmed ID

3897340

DOI: Digital Object Identifier

10.1016/s0735-1097(85)80106-6

Related Literature

Article Analysis
・Side Effects of protriptyline
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.