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Transdermally administered scopolamine vs. dimenhydrinate. I. Effect on nausea and vertigo in experimentally induced motion sickness.

Author: JänttiV, PyykköI, SchalénL

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Transdermal scopolamine and dimenhydrinate were both effective in reducing nausea and vertigo in volunteers experiencing motion sickness. Dimenhydrinate was more effective against nausea than one TTS-scopolamine patch, while two patches were needed for similar efficacy against vertigo.
Paper Details　
Original Abstract of the Article :
The effect of transdermally administered scopolamine (TTS-scopolamine) (2.5 cm2 surface area, one and two patches) and dimenhydrinate (100 mg) on experimental motion sickness was examined in 16 healthy volunteers in a randomized double-blind study. Nausea was induced by Coriolis manoeuvre and vertig...See full text at original site
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引用元：
https://doi.org/10.3109/00016488509182265

データ提供：米国国立医学図書館（NLM）

Motion Sickness: A Comparative Look at Transdermal Scopolamine and Dimenhydrinate

This research explores the effectiveness of two common medications for motion sickness - transdermally administered scopolamine and dimenhydrinate. It's like comparing different desert survival strategies, each with its own strengths and weaknesses. This study investigates the effectiveness of these medications in reducing nausea and vertigo induced by experimental motion sickness. It's like a controlled experiment in a desert laboratory, carefully assessing the effects of different treatments on various physiological responses.

Scopolamine and Dimenhydrinate: Effective Against Motion Sickness

The study found that both transdermal scopolamine and dimenhydrinate effectively reduced nausea and vertigo, demonstrating their effectiveness in mitigating motion sickness symptoms. It's like finding two different types of cacti, each offering a unique source of sustenance and protection in the harsh desert environment. While dimenhydrinate was slightly more effective against nausea, scopolamine, applied several hours before exposure, proved effective in reducing both nausea and vertigo.

Navigating the Desert of Motion Sickness

This study offers valuable information for individuals prone to motion sickness. It's like a guidebook to navigate the treacherous terrain of motion sickness, providing strategies for minimizing discomfort and maximizing enjoyment during travel. The study highlights the effectiveness of both transdermal scopolamine and dimenhydrinate, empowering travelers to choose the most suitable medication for their individual needs and preferences.

Dr.Camel's Conclusion

This research provides insights into the effectiveness of transdermal scopolamine and dimenhydrinate in managing motion sickness. It's like finding a reliable caravan route through the desert, offering safe passage and relief from discomfort. The study highlights the importance of considering individual needs and preferences when choosing a medication for motion sickness, ensuring a more enjoyable and comfortable travel experience.

Date :
  1. Date Completed 1985-09-04
  2. Date Revised 2019-07-16
Further Info :

Pubmed ID

4024909

DOI: Digital Object Identifier

10.3109/00016488509182265

Related Literature

Article Analysis
・Side Effects of dimenhydrinate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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