Debendox revisited.

Author: CampbellH, DaunceyM, ElbourneD, MutchL, SamphierM

Paper Details 
Original Abstract of the Article :
Two further studies re-examine the findings by Golding et al. (1983) in Oxford that mothers of children born with oral clefts had been more frequently prescribed Debendox (Bendectin) than had the mothers of matched controls. In Cardiff, 86 283 total births between 1965 and 1979 included 139 infants ...See full text at original site
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引用元:
https://doi.org/10.1111/j.1471-0528.1985.tb03046.x

データ提供:米国国立医学図書館(NLM)

Debendox: Unraveling the Mystery of Oral Clefts

Debendox, a medication used to treat morning sickness, was once suspected of being linked to an increased risk of oral clefts in newborns. This study re-examines the findings of previous research, which suggested a possible association between Debendox use during pregnancy and oral clefts. The researchers analyzed data from two independent cohorts, in Cardiff and Aberdeen, to assess the relationship between Debendox exposure and the occurrence of oral clefts. Their findings did not support the previous findings, suggesting that there may not be a causal link between Debendox use and oral clefts. This study is like a detective unraveling a mystery, searching for the truth behind a long-standing puzzle.

Debendox: Clearing the Air on a Controversial Medication

This research sheds light on a controversial medication, Debendox, and helps clarify the potential risks associated with its use during pregnancy. The findings from both Cardiff and Aberdeen cohorts did not support the previous findings of an association between Debendox and oral clefts, which is encouraging news for pregnant women seeking relief from morning sickness. This is like finding a hidden oasis in the desert of medical uncertainties, providing clarity and reassurance.

Pregnancy and Medications: Consulting Your Healthcare Provider

This study highlights the importance of thorough research and evidence-based decision-making in medicine. It underscores the need for pregnant women to consult with their healthcare providers regarding any medications they may need to take during pregnancy, ensuring that the benefits outweigh the risks. This research is like a guiding star, helping to navigate the complexities of pregnancy and medication use.

Dr.Camel's Conclusion

Like a camel navigating through the shifting sands of medical research, this study provides valuable insights into the safety of Debendox during pregnancy. By examining the evidence with a critical eye, researchers have helped to dispel previous concerns, offering reassurance to pregnant women and their healthcare providers. This research is a testament to the importance of scientific rigor and the ongoing quest for reliable information in medicine.

Date :
  1. Date Completed 1985-10-24
  2. Date Revised 2019-07-19
Further Info :

Pubmed ID

4027200

DOI: Digital Object Identifier

10.1111/j.1471-0528.1985.tb03046.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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