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Efficacy and side effects of lorazepam, oxazepam, and temazepam as sleeping aids in psychogeriatric inpatients.

Author: AuvinenJ, LamminsivuU, LinnoilaM, ViukariM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Lorazepam, oxazepam, and temazepam were effective in maintaining sleep in psychogeriatric inpatients. None of the drugs shortened sleep latency. Oxazepam and temazepam induced withdrawal insomnia, while lorazepam caused delayed and prolonged insomnia in some patients. Lorazepam and oxazepam had muscle relaxant side effects.
Paper Details　
Original Abstract of the Article :
The efficacy and side effects of 2 mg of lorazepam, 30 mg of oxazepam, and 20 mg of temazepam as sleeping aids were investigated in 20 psychogeriatric inpatients. The drugs were administered in a random order, double-blind, for 7 night each. All of these short half-life benzodiazepines proved effica...See full text at original site
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引用元：
https://doi.org/10.1159/000468424

データ提供：米国国立医学図書館（NLM）

A Night of Rest in a Desert of Insomnia: Evaluating Benzodiazepines for Sleep Disturbances

This research delves into the [world of psychogeriatrics], specifically exploring the effectiveness of [benzodiazepines] as [sleeping aids] for [elderly patients]. It's like navigating a vast desert of sleep disorders, seeking to find a solution for those struggling to find restful nights.

A Temporary Oasis: Benzodiazepines Provide Temporary Relief for Sleep Disturbances

The study investigated the [efficacy and side effects] of [lorazepam, oxazepam, and temazepam] in [20 psychogeriatric inpatients]. The researchers found that all three benzodiazepines were effective in [maintaining sleep], although they did not significantly reduce [initial sleep latency]. It’s like finding a temporary oasis in the desert of insomnia – a short-term solution that offers respite but may not address the underlying cause of sleep disturbances.

Navigating the Desert of Sleep: Considerations for Benzodiazepine Use

This research highlights the potential benefits and limitations of [benzodiazepines] for [sleep disturbances] in [elderly patients]. The researchers noted that [lorazepam and oxazepam] had [muscle relaxant side effects] after awakening. It's important to weigh the risks and benefits of benzodiazepines and to use them cautiously, especially in vulnerable populations. It’s like learning to navigate the shifting sands of sleep disturbances – understanding the potential side effects and limitations of medications is crucial for achieving restful nights.

Dr. Camel's Conclusion

This study sheds light on the effectiveness and potential side effects of benzodiazepines as sleep aids for elderly patients. The results highlight the need for careful consideration of the risks and benefits of these medications and for exploring alternative approaches to managing sleep disturbances in this population. It’s like finding a temporary respite in the desert of insomnia – a reminder that there's always more to learn about the complexities of sleep and the best ways to address sleep disturbances.
Date :
  1. Date Completed 1981-02-19
  2. Date Revised 2019-10-31
Further Info :

Pubmed ID

6108299

DOI: Digital Object Identifier

10.1159/000468424

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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