A suitable substitute for 4% cocaine before blind nasotracheal intubation: 3% lidocaine-0.25% phenylephrine nasal spray.

Author: GrossJ B, HartiganM L, SchafferD W

Paper Details 
Original Abstract of the Article :
To assess the efficacy of potential substitutes for cocaine as a topical anesthetic before nasal intubation, the authors performed a double-blind study comparing the hemodynamic effects of blind nasotracheal intubation in 75 patients receiving one of three nasal sprays: 4% cocaine (C), a mixture of ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/6207751

データ提供:米国国立医学図書館(NLM)

Finding Alternatives to Cocaine for Nasal Intubation

The field of [anesthesia] is always seeking ways to improve patient comfort and safety. This study explores potential replacements for cocaine, a traditional topical anesthetic used before nasal intubation. The researchers conducted a double-blind study comparing the effects of three nasal sprays: cocaine, lidocaine-phenylephrine, and phenylephrine alone. They found that lidocaine-phenylephrine was significantly more effective in reducing blood pressure and heart rate compared to the other two options. This discovery could have significant implications for patient care, potentially reducing the risk of complications associated with cocaine use.

Lidocaine-Phenylephrine Shows Promise as a Safer Alternative

The results clearly show that lidocaine-phenylephrine outperforms cocaine and phenylephrine alone in terms of hemodynamic effects, suggesting that it may be a safer and more effective alternative. This finding is particularly relevant in light of concerns about the potential side effects of cocaine. The study also highlights the importance of careful monitoring of vital signs during the procedure, as significant changes were observed in all groups.

A New Approach to Nasal Intubation

The findings suggest that lidocaine-phenylephrine may be a more desirable option for patients undergoing nasal intubation, potentially leading to improved safety and reduced discomfort. This is a significant step forward in the search for safer and more effective anesthesia techniques. While more research is needed to fully understand the long-term implications of this discovery, the results are promising and open new avenues for improving patient care in this area.

Dr.Camel's Conclusion

This study is a testament to the ongoing pursuit of safer and more effective medical practices. The findings suggest that lidocaine-phenylephrine may be a valuable addition to the anesthesiologist's toolkit, offering a potentially safer alternative to cocaine for nasal intubation. Just like a wise camel traversing the vast desert, researchers continue to explore new horizons in search of the most effective solutions for patients' well-being.

Date :
  1. Date Completed 1984-11-01
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

6207751

DOI: Digital Object Identifier

6207751

Related Literature

SNS
PICO Info
in preparation
Languages

English

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