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Immunogenicity and safety of heat-inactivated hepatitis B vaccine (CLB) in low risk human volunteers and in patients treated with chronic haemodialysis in the Netherlands.
Author: BrummelhuisH G, DeesP J, LelieP N, Reerink-BrongersE E, ReesinkH W, van AkenW G
Original Abstract of the Article :
The immunogenicity and safety of a heat-inactivated hepatitis B vaccine (HB-vaccine) were studied in healthy human volunteers (n = 471) at a low risk to be infected with hepatitis B virus (HBV) and in patients on chronic haemodialysis (n = 227), who were treated in hepatitis B free centres. After va...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/6228459
データ提供:米国国立医学図書館(NLM)
The Effectiveness and Safety of Hepatitis B Vaccine
Imagine a vast desert, where the heat and dryness can make life difficult. Now imagine a vaccine as a source of cool water, protecting people from a potentially dangerous disease. This study delves into the effectiveness and safety of a heat-inactivated hepatitis B vaccine. Researchers tested the vaccine on two groups of individuals: healthy volunteers and patients on chronic hemodialysis. They wanted to see how well the vaccine protected them from hepatitis B infection and if it caused any unwanted side effects.
The Vaccine's Protective Oasis
The study found that the vaccine was highly effective in both groups, with a significant majority developing antibodies against the hepatitis B virus. The researchers also observed that increasing the dosage of the vaccine for hemodialysis patients further enhanced their immune response. The study also confirmed that the vaccine had a very good safety profile with minimal side effects.
Navigating the Desert of Disease Prevention
This study highlights the importance of vaccination in protecting ourselves from infectious diseases. The researchers found that the hepatitis B vaccine is a safe and effective tool for preventing infection, especially for those at risk, like hemodialysis patients. This study reinforces the message that vaccination is a vital step in staying healthy and protecting ourselves from the harsh realities of infectious diseases.
Dr.Camel's Conclusion
The findings of this study are a welcome oasis in the desert of infectious disease prevention. It demonstrates the effectiveness and safety of the hepatitis B vaccine, offering crucial protection against a potentially serious illness. The study reminds us that vaccination is an essential tool for protecting our health and navigating the vast desert of infectious diseases.
Date :
- Date Completed 1984-02-24
- Date Revised 2008-11-21
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