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Comparative side effects of imipramine, benztropine, or their combination in patients receiving fluphenazine decanoate.

Author: NovemberM, ReardonG T, RifkinA, SirisS G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Patients taking fluphenazine decanoate experienced increased extrapyramidal side effects when switching from benztropine to imipramine. However, adding imipramine to fluphenazine decanoate and benztropine did not significantly increase anticholinergic side effects.
Paper Details　
Original Abstract of the Article :
Patients receiving fluphenazine decanoate who were switched from adjunctive benztropine to imipramine in a double-blind trial experienced marked exacerbations of extrapyramidal side effects. No substantial increase in anticholinergic side effects occurred, however, when imipramine was added to fluph...See full text at original site
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引用元：
https://doi.org/10.1176/ajp.140.8.1069

データ提供：米国国立医学図書館（NLM）

The Intricate Dance of Medications: A Comparative Study of Side Effects

Navigating the world of psychotropic medications can be like traversing a vast desert – a delicate balance is required to find the right path for each patient. This study focuses on the intricate relationship between three medications used to treat mental health conditions: imipramine, benztropine, and fluphenazine decanoate. Researchers are interested in understanding how these medications interact with each other and how they affect patients' experiences with side effects. The study's findings provide valuable insights into how to optimize treatment strategies and minimize adverse reactions.

Side Effects: Navigating the Shifting Sands of Medication

The study reveals a complex interplay between these medications, highlighting the importance of carefully considering potential side effects. Think of it like a camel caravan facing a shifting sandstorm – slight changes in the medication regimen can have a significant impact on the journey. This research underscores the need for meticulous observation and personalized care when managing patients with mental health conditions.

Finding the Right Path in the Desert of Mental Health

This study serves as a valuable reminder that navigating the desert of mental health requires a delicate balance and individualized approach. It is essential to work closely with healthcare providers to understand the potential side effects of medications and to adjust treatment plans accordingly. The findings of this study contribute to our understanding of the complex interplay between medications and can help us optimize treatment strategies for patients.

Dr. Camel's Conclusion

The study highlights the delicate balance that exists when prescribing psychotropic medications. Like a wise camel caravan leader, healthcare providers must carefully select and adjust medications to find the optimal path for each patient, minimizing side effects and maximizing benefits.

Date :
  1. Date Completed 1983-08-26
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6346910

DOI: Digital Object Identifier

10.1176/ajp.140.8.1069

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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