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Original Abstract of the Article :
A middle-aged diabetic woman after four weeks of chlorpropamide treatment developed cholestatic hepatitis with systemic manifestations of idiosyncratic reaction. After recovery, unintended rechallenge with the same drug induced a brisk exacerbation of the symptoms and signs that reversed completely ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/BF02582093
データ提供:米国国立医学図書館(NLM)
Glibenclamide: A Beacon of Hope in a Desert of Drug Reactions
The world of medication can sometimes feel like a vast desert, with unexpected side effects lurking around every corner. This case study presents a fascinating journey through the challenges of drug reactions, showcasing the effectiveness of glibenclamide (glyburide) in a patient who experienced severe idiosyncratic reactions to both chlorpropamide and tolbutamide. The study highlights the importance of individual patient responses to medication and underscores the need for careful monitoring and alternative treatments when necessary.
The Importance of Individualized Therapy
This case study exemplifies the individualistic nature of drug responses. What works for one person may not work for another. It emphasizes the need for close observation and adjustment of treatment plans based on individual patient responses.
Navigating the Desert of Drug Reactions: A Collaborative Journey
This study emphasizes the collaborative nature of healthcare. When a patient experiences unexpected reactions, healthcare providers must work together to find the best course of action. The success of glibenclamide in this case demonstrates the importance of open communication and creative solutions in the face of adversity.
Dr.Camel's Conclusion
This study reminds us that we must approach medication with a cautious optimism. The desert of drug reactions can be daunting, but with careful monitoring and a collaborative spirit, we can navigate this challenging terrain and find the oasis of effective treatment for each individual patient.
Date :
- Date Completed 1985-04-11
- Date Revised 2019-11-11
Further Info :
Related Literature
English
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