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Immunogenicity and safety of a plasma-derived heat-inactivated hepatitis B vaccine (CLB). Studies in volunteers at a low risk of infection with hepatitis B virus.

Author: DeesP J, LelieP N, Reerink-BrongersE E, ReesinkH W, de Jong-van ManenS T

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A plasma-derived, heat-inactivated hepatitis B vaccine was found to be safe and immunogenic in 471 healthy volunteers. The vaccine was well-tolerated, with no serious side effects reported.
Paper Details　
Original Abstract of the Article :
The safety and immunogenicity of a plasma-derived heat-inactivated hepatitis B vaccine (CLB) were evaluated in 471 healthy human volunteers, who, both in their occupations and in their private lives, had been at minimal risk of being infected with hepatitis B virus. The first 202 individuals receive...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1093/oxfordjournals.aje.a113936

データ提供：米国国立医学図書館（NLM）

Safety and Immunogenicity of a Hepatitis B Vaccine

The world of vaccines is a bustling market, constantly searching for the best ways to protect against infectious diseases. This study focuses on a plasma-derived heat-inactivated hepatitis B vaccine, evaluating its safety and effectiveness in individuals at low risk of hepatitis B infection. The researchers found that the vaccine was well-tolerated and effective, with high rates of antibody production.

Developing a Safe and Effective Vaccine

This study highlights the importance of rigorous testing to ensure the safety and effectiveness of vaccines. The findings contribute to a growing body of evidence supporting the use of this particular vaccine in low-risk populations.

Understanding Vaccine Safety and Efficacy

This research underscores the importance of understanding the nuances of vaccine safety and efficacy. Just like a desert traveler needs to be aware of potential hazards, individuals should be informed about the potential benefits and risks associated with different vaccines.

Dr. Camel's Conclusion

This research emphasizes the crucial role of scientific investigation in ensuring the safety and efficacy of vaccines, paving the way for a healthier and more protected future.

Date :
  1. Date Completed 1984-11-28
  2. Date Revised 2019-05-11
Further Info :

Pubmed ID

6496450

DOI: Digital Object Identifier

10.1093/oxfordjournals.aje.a113936

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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