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[Experimental and clinical evaluation of cefotetan in pediatrics].

Author: IwaiN, MizoguchiF, NakamuraH, SasakiA, TanedaY

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
English AbstractA summary of a research paper/publication written in English for a wider audience.

Overview

Cefotetan (CTT) was effective in treating 91.7% of 42 children with bacterial infections. The eradication rate was 92.3% for all strains except for 1 strain of H. influenzae and S. faecalis. No side effects were recognized, though abnormal laboratory findings were observed in 3 cases.
Paper Details　
Original Abstract of the Article :
Fundamental and clinical studies of cefotetan (CTT) were made in pediatric field and the following results were obtained. Antimicrobial activity MIC80 values of CTT against clinically isolated S. aureus (32 strains), E. coli (33 strains) and K. pneumoniae (33 strains) were 25, 0.1 and 0.1 microgram/...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6581333

データ提供：米国国立医学図書館（NLM）

Cefotetan: A New Oasis in the Desert of Pediatric Infections

Navigating the desert of pediatric infections can be a daunting task, requiring a keen eye for effective treatments and a gentle touch in administering them. This study explores the use of cefotetan (CTT), a new antibiotic, in treating infections in young patients. The researchers conducted a series of studies, akin to a caravan meticulously exploring a new route, to assess the antimicrobial activity, pharmacokinetics, and clinical efficacy of CTT in children. Their objective was to determine if CTT could be a reliable oasis in the desert of pediatric infections, offering a safe and effective treatment option.

A Promising Oasis in the Desert of Pediatric Infections

The study's findings, like a well-placed oasis in a vast desert, revealed that CTT showed significant antimicrobial activity against various bacterial strains commonly found in pediatric infections. The researchers observed favorable pharmacokinetic properties, indicating that CTT was effectively absorbed and distributed in the body. The clinical trial demonstrated a high efficacy rate, with CTT successfully treating a wide range of infections. These findings suggest that CTT could be a valuable addition to the pediatric arsenal for combating infections.

Navigating the Challenges of Using CTT

While the study's findings are promising, using CTT, like any oasis in the desert, comes with certain considerations. The researchers noted that while CTT was generally well-tolerated, some children experienced mild side effects. It is crucial for healthcare professionals to carefully monitor patients receiving CTT and adjust treatment strategies as needed. Further research is needed to explore the long-term effects of CTT and optimize its use in children.

Dr. Camel's Conclusion

This study offers a valuable guide in navigating the desert of pediatric infections. The potential of CTT as a safe and effective treatment option for children is promising. As a researcher, I am always eager to find new solutions for those who need them most, especially our youngest patients. This study represents a significant step forward in the quest for better treatments for pediatric infections.

Date :
  1. Date Completed 1984-02-14
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

6581333

DOI: Digital Object Identifier

6581333

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Languages

Japanese

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