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Bronchodilator response to oral aminophylline and terbutaline versus aerosol albuterol in patients with chronic obstructive pulmonary disease.

Author: ShimC S, WilliamsM H

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Albuterol aerosol was more effective than oral administration of aminophylline or terbutaline sulfate in 17 patients with stable chronic obstructive pulmonary disease. No patients experienced side effects during aerosol therapy.
Paper Details　
Original Abstract of the Article :
Bronchodilator efficacy of oral administration of aminophylline (400 mg) and terbutaline sulfate (5 mg) was compared with inhalation of three puffs of albuterol sulfate in 17 patients with stable chronic obstructive pulmonary disease in a double-blind crossover study. Two hours after either form of ...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9343(83)90459-x

データ提供：米国国立医学図書館（NLM）

Aerosol Albuterol: A Superior Choice for Bronchodilation in Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a serious lung condition that can significantly impair breathing. This study compares the bronchodilator efficacy of oral aminophylline and terbutaline sulfate to aerosol albuterol in patients with stable COPD. The authors found that aerosol albuterol was significantly more effective in increasing forced expiratory volume in one second (FEV1) compared to oral medications, while also being free of side effects.

Aerosol Albuterol: A More Effective and Tolerable Bronchodilator for COPD

This research underscores the superiority of aerosol albuterol as a bronchodilator for COPD patients. The study found that aerosol albuterol provided a more pronounced and sustained improvement in lung function, while also being better tolerated than oral medications.

Managing COPD: Choosing the Right Treatment and Lifestyle Modifications

COPD management involves a combination of appropriate medication and lifestyle modifications. This research emphasizes the importance of considering aerosol albuterol as a preferred bronchodilator for COPD patients. Alongside medication, lifestyle changes such as smoking cessation, avoiding irritants, and regular exercise can help improve lung function and quality of life.

Dr. Camel's Conclusion

Just as a camel adapts to the dry desert air, patients with COPD must find ways to navigate the challenges of their condition. This study highlights the importance of choosing the right bronchodilator, demonstrating the superior efficacy and tolerability of aerosol albuterol. This research is like a cool breeze in the arid landscape of COPD, reminding us of the importance of finding effective solutions to improve the lives of those affected by this debilitating disease.
Date :
  1. Date Completed 1983-11-23
  2. Date Revised 2019-06-27
Further Info :

Pubmed ID

6624778

DOI: Digital Object Identifier

10.1016/0002-9343(83)90459-x

Related Literature

Article Analysis
・Side Effects of albuterol oral inhalation
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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