Development of tolerance to the side effects of primidone.

Author: CloydJ C, LeppikI E, MillerK

Paper Details 
Original Abstract of the Article :
Side effects and antiepileptic drug levels were measured during initiation of and chronic treatment with primidone (PRM). A significant change in the toxicity/serum level ratio was observed 6 h after the initial PRM dose. The amount of toxicity manifested by patients receiving PRM as their initial a...See full text at original site
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引用元:
https://doi.org/10.1097/00007691-198406000-00010

データ提供:米国国立医学図書館(NLM)

Primidone: A New Oasis in the Desert of Epilepsy Treatment

The desert of [epilepsy treatment] is a vast and unforgiving landscape, where patients often struggle with [seizure control and medication side effects]. This study, like a well-equipped caravan navigating the dunes, focuses on [primidone (PRM)], a medication used to treat epilepsy. The researchers, like astute desert explorers, sought to understand how [tolerance develops to the side effects of PRM] over time.

A Tale of Tolerance: Adapting to the Desert

The researchers, like seasoned desert travelers, observed that [patients quickly developed tolerance to the side effects of PRM], even when previously treated with other antiepileptic drugs. This finding, like a hidden spring in the dunes, suggests that [PRM may be a viable treatment option for epilepsy], even for patients with prior exposure to other medications.

Navigating the Desert of Treatment Options: A Personalized Approach

This study, like a guidepost in the desert, provides valuable insights for patients and healthcare providers seeking effective treatment options for epilepsy. The researchers emphasize the importance of [individualized treatment plans] that consider the patient's medical history, tolerance to medications, and potential side effects.

Dr.Camel's Conclusion

The desert of epilepsy treatment is filled with challenges, but this study, like a new trail, offers a promising avenue for patients seeking effective and well-tolerated medication options.

Date :
  1. Date Completed 1984-08-17
  2. Date Revised 2019-09-04
Further Info :

Pubmed ID

6740738

DOI: Digital Object Identifier

10.1097/00007691-198406000-00010

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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