Diflunisal. A new oral analgesic with an unusually long duration of action.

Author: BeaverW T, ForbesJ A, NeilsonG B, ShacklefordR W, WhiteE H, WhiteR W

Paper Details 
Original Abstract of the Article :
The analgesic efficacy of single 500- and 1,000-mg doses of diflunisal (Dolobid), a new nonsteroidal anti-inflammatory analgesic, was compared in a double-blind study with that of acetaminophen, 600 mg, the combination of acetaminophen, 600 mg, with codeine phosphate, 60 mg, and placebo in 159 oral ...See full text at original site
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引用元:
https://doi.org/10.1001/jama.248.17.2139

データ提供:米国国立医学図書館(NLM)

A Long-Lasting Relief: Diflunisal for Analgesia

The world of [pain management] is constantly searching for effective and long-lasting pain relievers. This study investigates the analgesic efficacy of [diflunisal], a [new nonsteroidal anti-inflammatory analgesic], compared to [acetaminophen] and [acetaminophen with codeine] in patients undergoing [oral surgery]. It's like a camel caravan traversing a harsh desert – pain can be a debilitating obstacle, and finding the right pain relief can be a long and arduous journey.

A Steady Stream of Relief: Diflunisal's Long Duration

The study found that [diflunisal was significantly more effective than acetaminophen alone] and [produced peak analgesia comparable to that of the acetaminophen-codeine combination]. It's like finding a steady stream of water in the desert – diflunisal provided lasting relief for pain, outlasting the effects of other analgesics. The researchers also found that [diflunisal had an unusually long duration of analgesic action].

Navigating the Desert of Pain Management: Choosing the Right Path

This study offers valuable insights into the potential of [diflunisal] for managing pain. It's like finding a new path through the desert – diflunisal could be a valuable option for patients seeking long-lasting pain relief. This study highlights the importance of [careful consideration] of the different pain management options available.

Dr. Camel's Conclusion

The desert of pain can be a harsh and unforgiving place, but this study offers a glimmer of hope for those seeking lasting relief. Diflunisal's long duration of action could be a valuable asset for patients seeking effective pain management, providing a steady stream of comfort throughout their journey. While further research is needed to fully understand the implications of diflunisal, this study serves as a reminder that the search for effective pain relief continues, and new discoveries are always on the horizon.

Date :
  1. Date Completed 1982-12-03
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

6750171

DOI: Digital Object Identifier

10.1001/jama.248.17.2139

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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