Paper Details

  1. Home
  2. Paper Details

[Pirprofen, indomethacin and placebo in ankylosing spondylitis. Double-blind comparison].

Author: ChadriH A, JajicI, NekoraA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Pirprofene was more effective than indomethacin and placebo in treating ankylosing spondylitis, with 87% of patients showing satisfactory results compared to 77% and 29% respectively. However, a significant number of patients in all groups experienced side effects.
Paper Details　
Original Abstract of the Article :
One hundred and four patients with ankylosing spondylitis were involved in a comparative trial carried out in one single centre. They were given either pirprofene (1000 mg/day), indomethacin (125 mg/day) or a placebo for 6 consecutive weeks. Response to treatment was assessed after 1, 2, 4 and 6 wee...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/6752873

データ提供：米国国立医学図書館（NLM）

Treating Ankylosing Spondylitis: Comparing Pirprofen and Indomethacin

Ankylosing spondylitis, a chronic inflammatory condition affecting the spine, presents a significant challenge for healthcare professionals. This study explores the effectiveness of two anti-inflammatory drugs, pirprofen and indomethacin, in managing the symptoms of this condition. Think of these drugs as two different types of desert plants, each offering its own unique benefit in combating the inflammation that characterizes ankylosing spondylitis.

The researchers conducted a double-blind trial involving 104 patients with ankylosing spondylitis. They compared the effectiveness of pirprofen and indomethacin to a placebo. The results showed that both pirprofen and indomethacin were significantly more effective than placebo in improving the symptoms of ankylosing spondylitis.

Pirprofen and Indomethacin: Effective Options for Ankylosing Spondylitis

This study provides evidence that pirprofen and indomethacin are effective treatments for ankylosing spondylitis. These medications offer relief from the pain and stiffness associated with this condition. Imagine these drugs as two powerful desert winds, easing the discomfort and bringing a sense of calm to patients with ankylosing spondylitis.

Managing Ankylosing Spondylitis: A Multifaceted Approach

Treating ankylosing spondylitis often requires a combination of approaches, including medication, exercise, and lifestyle modifications. While this study provides valuable insights into the effectiveness of specific medications, it's important to remember that managing this condition is a lifelong journey that requires a collaborative effort between patients and healthcare providers.

Dr.Camel's Conclusion

This study offers a glimpse into the world of ankylosing spondylitis, a condition that can be both challenging and debilitating. While there are no quick fixes, this research reveals that pirprofen and indomethacin offer hope to patients seeking relief from the symptoms of this condition. Imagine these drugs as two powerful desert winds, easing the discomfort and bringing a sense of calm to patients.

Date :
  1. Date Completed 1982-12-18
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

6752873

DOI: Digital Object Identifier

6752873

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.