Paper Details 
Original Abstract of the Article :
The effects of chlorpropamide on serum lipids, lipoproteins and fractional triglyceride removal have been studied over 12 months on 10 maturity onset diabetics not controlled on diet alone. Similar studies were carried out in 6 maturity onset diabetics who had failed to respond to sulphonylureas and...See full text at original site
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引用元:
https://doi.org/10.1007/BF00422249

データ提供:米国国立医学図書館(NLM)

Chlorpropamide and Insulin: A Tale of Two Diabetes Treatments

Diabetes, a condition that disrupts the body's ability to regulate blood sugar, is a common ailment that has plagued humans for centuries. This study delves into the effects of two diabetes medications, chlorpropamide and insulin, on serum lipids and lipoproteins. The study examines the impact of these medications on various lipid parameters, providing valuable insights into their long-term effects. This research is like a journey through a desert, uncovering the unique effects of different treatments on the body's delicate metabolic balance.

Chlorpropamide: A Fickle Oasis

The study found that chlorpropamide initially reduced serum and VLDL triglycerides, but this effect waned over time. The medication, like a desert oasis that dries up during a drought, failed to maintain its initial benefits.

Insulin: A Lasting Oasis

In contrast, insulin was more effective in reducing serum and VLDL triglycerides, with a lasting impact on lipid parameters. This discovery, like finding a permanent oasis in a desolate landscape, offers a promising treatment option for diabetes.

The Importance of Long-Term Effects

This research highlights the importance of considering the long-term effects of diabetes medications. Just as a desert traveler must carefully consider the sustainability of an oasis, healthcare providers must weigh the long-term benefits and drawbacks of different treatments.

Dr. Camel's Conclusion

This study underscores the complexities of diabetes management. The findings highlight the need for careful monitoring and individualized treatment approaches, tailored to each patient's unique needs and circumstances.

Date :
  1. Date Completed 1978-12-20
  2. Date Revised 2019-08-16
Further Info :

Pubmed ID

700275

DOI: Digital Object Identifier

10.1007/BF00422249

Related Literature

SNS
PICO Info
in preparation
Languages

English

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