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Effects of tienilic acid used alone and in association with triamterene or amiloride on urinary excretion of electrolytes.
Author: AmbrosioniE, BasseinL, LusaA M, MagnaniB, TartagniF
Original Abstract of the Article :
The K-sparing effects of amiloride (A) and triamterene (T) associated with tienilic acid (C) are studied, along with their effects on diuresis and on the urinary excretion of uric acid, Mg, Na, Cl, P, and Ca. Eighteen hospitalized patients, divided into two groups of nine, received the following dos...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/7287241
データ提供:米国国立医学図書館(NLM)
Tienilic Acid and Its Effects on Electrolyte Excretion
The human body is a complex and intricate machine, much like the delicate balance of a desert ecosystem. This study delves into the intricate world of electrolytes, exploring the effects of tienilic acid, a diuretic medication, on their excretion in urine. The study, akin to a meticulous desert explorer charting an unknown territory, investigates the effects of tienilic acid in combination with two other medications, amiloride and triamterene, both known for their potassium-sparing properties. The researchers, like seasoned desert guides, carefully observed the effects of different dosages of these medications on various electrolytes, including potassium, magnesium, sodium, and chloride, providing valuable insights into their potential impact on fluid balance.
Unveiling the Complexities of Electrolyte Regulation
The study reveals that the combination of tienilic acid with higher doses of amiloride and triamterene resulted in a significant potassium-sparing effect, as well as minor effects on the excretion of other electrolytes, such as magnesium and chloride. This finding, much like the discovery of a hidden oasis in the desert, highlights the complex interplay between different medications and their impact on the delicate balance of electrolytes in the body.
Navigating the Oasis of Electrolyte Balance: A Guide for Patients
Remember, just as a camel adapts to the harsh desert environment, our bodies adapt to changes in electrolyte levels. It's crucial to be aware of the potential effects of medications on electrolytes, especially if you're taking diuretics or potassium-sparing medications. Consult with your healthcare provider if you have any concerns, and be sure to follow their instructions carefully. Maintaining proper electrolyte balance is essential for overall health and well-being, just as a well-hydrated camel thrives in the desert.
Dr. Camel's Conclusion
This study, like a cool breeze in the desert, provides valuable insights into the intricate world of electrolytes. Understanding the impact of medications on their balance is essential for ensuring optimal health, especially in individuals taking diuretics or other medications that affect electrolyte levels. Just as a camel relies on its ability to regulate water and electrolytes in the harsh desert environment, we must be mindful of these crucial aspects of human physiology.
Date :
- Date Completed 1981-12-15
- Date Revised 2013-11-21
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English
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