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Oral and inhaled salbutamol in the prevention of exercise-induced bronchospasm.

Author: FrancisP W, KrastinsI R, LevisonH

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Oral salbutamol and salbutamol aerosol were equally effective in preventing exercise-induced bronchospasm (EIB) in asthmatic children. Oral salbutamol was clinically effective in preventing EIB for 4.9 to 5.8 hours.
Paper Details　
Original Abstract of the Article :
Oral salbutamol in a dose 0.15 mg/kg of body weight was compared to a total dose of 0.2 mg of salbutamol aerosol in its ability to produce bronchodilation and to prevent exercise-induced bronchospasm (EIB) in 16 asthmatic children in a single-blind crossover study. The degree of bronchodilation seen...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/7402771

データ提供：米国国立医学図書館（NLM）

Salbutamol for Exercise-Induced Bronchospasm: A Tale of Two Delivery Methods

Exercise-induced bronchospasm (EIB), a common problem for individuals with asthma, can significantly impact physical activity and quality of life. This research explores the effectiveness of salbutamol, a bronchodilator medication, in preventing EIB, comparing two different delivery methods: oral and inhaled. Think of the airways as tunnels in a vast desert, where a sudden narrowing of the tunnels can make breathing difficult. This research explores different ways to widen these tunnels and improve airflow.

Delivering Relief: Oral vs. Inhaled Salbutamol

The study found that both oral and inhaled salbutamol were effective in preventing EIB in asthmatic children. However, the inhaled route demonstrated a faster onset of action, fewer side effects, and greater protection against EIB, particularly in smaller airways. This suggests that the inhaled route may be preferred for individuals with EIB. It is like having two different tools for clearing sand from a desert path: one is slower and less precise, while the other is faster and more efficient.

Breathing Easier: A Guide for Asthma Management

For individuals with asthma, it is crucial to manage their condition and prevent EIB. This research highlights the importance of choosing the right delivery method for salbutamol, taking into account individual needs and preferences. Regular exercise and proper medication management can help individuals with asthma live active and fulfilling lives. It is like preparing for a long trek through a desert, ensuring that you have the right supplies and tools to navigate the challenges ahead.

Dr.Camel's Conclusion

This research provides valuable insights into the effectiveness of salbutamol in preventing EIB. The study highlights the importance of considering different delivery methods and the potential benefits of inhaled salbutamol for individuals with EIB. It is a reminder that the desert of asthma management requires careful navigation and the right tools for a comfortable and fulfilling journey.

Date :
  1. Date Completed 1980-10-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7402771

DOI: Digital Object Identifier

7402771

Related Literature

Article Analysis
・Side Effects of albuterol oral inhalation
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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