Paper Details

  1. Home
  2. Paper Details

Use of recombinant interferon alfa-2b in the treatment of basal cell carcinoma.

Author: ChimentiS, Di CristofaroS, FargnoliM C, PerisK, TorloneG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Intra- and perilesional injections of interferon alfa-2b were effective in treating basal cell carcinoma (BCC), with a complete response rate of 67.1% and a partial response rate of 23.6%. Side effects were reversible with the use of paracetamol.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Several neoplasms including cutaneous T-cell lymphomas, malignant melanoma and Kaposi's sarcoma have been successfully treated with systemic or intralesional interferons (IFNs). Recently, intralesional alpha-IFN has also been employed in the treatment of basal cell carcinoma (BCC). OBJE...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1159/000246688

データ提供：米国国立医学図書館（NLM）

Fighting Skin Cancer: A New Weapon Against Basal Cell Carcinoma

Like a persistent desert sandstorm, basal cell carcinoma (BCC) is a common and potentially dangerous type of skin cancer. This research explores the potential of interferon alfa-2b, a naturally occurring substance that helps regulate the immune system, as a treatment for BCC.

The researchers treated a group of patients with BCC using intra- and perilesional injections of interferon alfa-2b, delivering the treatment directly to the cancerous area. They aimed to evaluate the effectiveness and safety of this approach.

Their findings indicate that interferon alfa-2b can be an effective treatment for BCC, achieving complete or partial responses in a significant number of patients. While some side effects were observed, they were generally mild and reversible.

A New Frontier in Skin Cancer Treatment: A Glimpse of Hope

The study suggests that interferon alfa-2b could offer a valuable alternative treatment option for BCC, potentially expanding the therapeutic arsenal for this common skin cancer.

Protecting Our Skin: A Guide to Skin Cancer Prevention

The study underscores the importance of sun protection, regular skin checks, and early detection in preventing and managing skin cancer. Consult with a healthcare professional for personalized advice on skin cancer prevention and early detection strategies.

Dr. Camel's Conclusion

This study, like a desert mirage that turns into a real oasis, offers a promising new treatment approach for BCC. The findings highlight the potential of interferon alfa-2b as a valuable weapon in the fight against this common form of skin cancer.

Date :
  1. Date Completed 1995-08-10
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

7599384

DOI: Digital Object Identifier

10.1159/000246688

Related Literature

Article Analysis
・Side Effects of interferon alfa-2b injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.