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Effects of trifluoperazine on synaptically evoked potentials and membrane properties of CA1 pyramidal neurons of rat hippocampus in situ and in vitro.

Author: AgopyanN, KrnjevićK

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Trifluoperazine, a phenothiazine antipsychotic, inhibited hippocampal activity by modulating calcium/calmodulin-dependent kinase and protein kinase C activity, leading to changes in chloride conductance and synaptic currents.
Paper Details　
Original Abstract of the Article :
The effects of trifluoperazine (TFP), a phenothiazine antipsychotic, on hippocampal activity were studied in the CA1 subfield, both in situ and in slices. In the extracellular studies in situ and in vitro, both somatic population spikes and dendritic excitatory postsynaptic potentials (EPSP) fields ...See full text at original site
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引用元：
https://doi.org/10.1002/syn.890130103

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1993-03-02
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

7678946

DOI: Digital Object Identifier

10.1002/syn.890130103

Related Literature

Article Analysis
・Effects of trifluoperazine
SNS
PICO Info
in preparation
Languages

English

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