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A comparative trial of large doses of ketoprofen and indomethacin in the treatment of rheumatoid arthritis.

Author: El-GhobareyA F, HadidiT, HamidH A, MavrikakisM, RennieJ A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Ketoprofen (300 mg/day) and indomethacin (150 mg/day) had similar subjective effects on pain in patients with rheumatoid arthritis. Objectively, ketoprofen may be more effective in reducing the articular index, suggesting a superior analgesic effect.
Paper Details　
Original Abstract of the Article :
A 4-weeks' double-blind, crossover study in 30 patients with definite or classical rheumatoid arthritis is reported using 300 mg ketoprofen per day and 150 mg indomethacin per day. Both drugs had similar effects upon the patients' subjective improvement of pain. Objectively, the results also suggest...See full text at original site
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引用元：
https://doi.org/10.1185/03007997609111999

データ提供：米国国立医学図書館（NLM）

Ketoprofen vs. Indomethacin for Rheumatoid Arthritis: A Quest for Effective Pain Relief

This study compares the effectiveness of large doses of ketoprofen and indomethacin in treating rheumatoid arthritis, a chronic autoimmune disease characterized by inflammation and pain in the joints. Researchers conducted a double-blind crossover study in 30 patients with rheumatoid arthritis, finding that both drugs offered similar subjective pain relief. However, ketoprofen demonstrated superior effectiveness in reducing the articular index, suggesting a potentially stronger analgesic effect. The study suggests that ketoprofen, in high dosages, could be a promising option for managing rheumatoid arthritis pain.

Finding Relief in the Desert of Rheumatoid Arthritis: Ketoprofen as a Potential Solution

This study offers a potential new path for managing the persistent pain associated with rheumatoid arthritis, a condition that can feel like a relentless desert trek. The researchers found that ketoprofen showed a stronger analgesic effect compared to indomethacin, offering a glimmer of hope for those seeking relief from this debilitating disease.

Navigating the Desert of Pain: Seeking Effective Treatments

This study highlights the ongoing quest for effective treatments for rheumatoid arthritis, a condition that can significantly impact a person's quality of life. It's like searching for a safe and reliable path through a vast and unforgiving desert. The researchers found that ketoprofen showed promising results, offering a potential oasis of relief for those suffering from rheumatoid arthritis.

Dr. Camel's Conclusion

This study suggests that ketoprofen could be a promising alternative for managing the pain associated with rheumatoid arthritis, offering a potentially more effective solution. It's like finding a hidden oasis in the desert of pain, providing a haven of relief and comfort for those suffering from this debilitating disease. Further research is needed to fully understand the long-term benefits of ketoprofen in managing rheumatoid arthritis, potentially leading to new and improved treatment strategies.

Date :
  1. Date Completed 1977-02-24
  2. Date Revised 2019-09-07
Further Info :

Pubmed ID

793780

DOI: Digital Object Identifier

10.1185/03007997609111999

SNS
PICO Info
in preparation
Languages

English

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