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Clonidine and lidocaine inhibition of isoflurane-induced tachycardia in humans.
Author: NambaH, NamikiA, TanakaS, TsuchidaH
Original Abstract of the Article :
A rapid increase in isoflurane concentration can induce tachycardia and hypertension and increase plasma catecholamine concentrations. To investigate a possible mechanism, we measured hemodynamic responses to isoflurane administered via mask; we also administered clonidine for premedication, lidocai...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/00000542-199412000-00007
データ提供:米国国立医学図書館(NLM)
Isoflurane-Induced Tachycardia: A Complex Dance of Chemicals
In the world of anesthesia, we navigate a delicate balance of chemicals to induce a state of controlled unconsciousness. Isoflurane, a commonly used anesthetic agent, can sometimes trigger an unwanted side effect: tachycardia, or a rapid heartbeat. This research investigates this phenomenon, examining the interplay of various drugs on the cardiovascular system.
Researchers administered isoflurane via a mask to their subjects and carefully monitored their hemodynamic responses. They then explored the effects of different medications, including clonidine, lidocaine, and intravenous lidocaine, on these responses. The results reveal a complex interplay of chemicals, with each drug influencing the hemodynamic response in unique ways.
Understanding the Chemical Symphony: A Key to Better Anesthesia
This study provides valuable insight into the mechanisms underlying isoflurane-induced tachycardia. Think of it like a complex musical composition with each drug acting as a different instrument. By understanding how these instruments interact, we can fine-tune our approach to anesthesia, ensuring a smoother and safer experience for our patients.
A Safer Journey: Navigating the Anesthetic Desert
This research highlights the importance of carefully considering the potential side effects of anesthetic agents and the role of various medications in mitigating these effects. It reminds us that the journey through the anesthetic desert requires meticulous planning and a deep understanding of the terrain we are navigating.
Dr.Camel's Conclusion
This research delves into the complex interplay of chemicals during anesthesia, revealing the underlying mechanisms of isoflurane-induced tachycardia. By understanding these dynamics, we can strive for safer and more efficient anesthetic practices, ensuring a smooth and comfortable journey for our patients through the desert of anesthesia.
Date :
- Date Completed 1995-01-10
- Date Revised 2019-06-28
Further Info :
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English
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