[Plasmatic concentrations of fluoxetine, pharmacokinetics, therapeutic response and side effects].

Author: AlvárezE, Pérez BlancoJ, Pérez SolaV, QueraltoJ M

Paper Details 
Original Abstract of the Article :
The kinetics of fluoxetine and possible relations between the drug's plasmatic concentration and therapeutic response and side effects were evaluated in a sample of 66 depressive patients, 26 men and 40 women, average age 46.6 years (SD = 14.1), diagnosed according to DSM-III criteria and evaluated ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8213289

データ提供:米国国立医学図書館(NLM)

Fluoxetine: Exploring the Relationship Between Plasma Concentration and Therapeutic Response

The field of psychopharmacology is constantly seeking to optimize the use of medications for mental health conditions. This study investigates the pharmacokinetics of fluoxetine, a commonly prescribed antidepressant, and examines the relationship between plasma concentration and therapeutic response in patients with depression. The study aimed to determine whether there is a correlation between fluoxetine levels in the blood and the effectiveness of treatment.

Fluoxetine's Dynamics: A Look at Plasma Concentration and Therapeutic Response

The study findings suggest that while there is no direct linear correlation between fluoxetine plasma concentration and therapeutic response, there appears to be a threshold below which therapeutic efficacy may be compromised. This research provides valuable insights into the pharmacokinetics of fluoxetine and highlights the importance of individualizing treatment approaches to maximize therapeutic benefits.

Managing Depression: Seeking Personalized Care

If you are taking fluoxetine for depression, it's important to work closely with your doctor to monitor your progress and adjust treatment as needed. Open communication and a personalized approach to treatment are essential for ensuring that you receive the optimal care for your individual needs. By actively engaging in your healthcare journey, you can maximize the effectiveness of fluoxetine and achieve a greater sense of well-being.

Dr.Camel's Conclusion

Imagine a desert where the effectiveness of fluoxetine is like a mirage, shimmering on the horizon, but sometimes elusive. This research reveals that while the concentration of fluoxetine in the blood may not directly correlate with therapeutic response, there is a minimum level needed for optimal effectiveness. It's like finding a hidden wellspring within the desert, ensuring a steady supply of medication to quench the thirst of depression.

Date :
  1. Date Completed 1993-11-18
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8213289

DOI: Digital Object Identifier

8213289

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