Paper Details 
Original Abstract of the Article :
Scanning electron microscopy and light microscopy have been used to study changes to the vaginal epithelium induced by exogenous hormones and clomiphene citrate (CC) administered to ovariectomised rats. Oestrogen (E2) administration resulted in epithelial cell proliferation and keratinisation. The a...See full text at original site
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引用元:
https://doi.org/10.1159/000147517

データ提供:米国国立医学図書館(NLM)

Clomiphene Citrate: A Unique Impact on the Vaginal Epithelium

This study investigates the effects of [clomiphene citrate (CC)] on the [vaginal epithelium] of ovariectomized rats, examining its impact compared to the effects of estrogen. Using both scanning electron microscopy and light microscopy, the researchers found that while CC stimulated cell proliferation, it did not induce keratinization to the same extent as estrogen. This unique effect on vaginal morphology highlights the specific actions of CC and its potential implications for reproductive health.

A Unique Effect: Clomiphene Citrate's Influence on Vaginal Morphology

The study revealed that [CC] has a [retarded oestrogenic action] on the vaginal epithelium, stimulating cell proliferation but not fully replicating the effects of estrogen. This observation contributes to the understanding of the specific actions of CC and its potential applications in reproductive health.

Navigating Reproductive Health: A Complex Landscape

This study highlights the need for careful consideration of the [specific actions and potential implications of CC] in reproductive health. The findings suggest that CC may have unique effects on the vaginal epithelium, warranting further investigation to fully understand its long-term impact on reproductive function.

Dr.Camel's Conclusion

The world of reproductive health is like a desert landscape, with its own unique flora and fauna. This research sheds light on the specific actions of clomiphene citrate, a compound that, like a mirage, can create a different image in the landscape of the vaginal epithelium. Further exploration is needed to fully understand the implications of these effects for reproductive health.

Date :
  1. Date Completed 1994-02-03
  2. Date Revised 2019-08-21
Further Info :

Pubmed ID

8273442

DOI: Digital Object Identifier

10.1159/000147517

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Languages

English

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