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A dose-response analysis of the subjective, psychomotor and physiological effects of intravenous morphine in healthy volunteers.

Author: CoalsonD W, FlemmingD, LichtorJ L, ThompsonW K, ZacnyJ P

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

In a study of 12 healthy volunteers, morphine was found to increase feelings of stimulation, high, sedation, spaced out, and drunken. Morphine also impaired reaction time, digit symbol substitution, and Maddox wing, but not eye-hand coordination.
Paper Details　
Original Abstract of the Article :
The purpose of this study was to characterize the subjective, psychomotor and physiological effects of morphine in healthy volunteers. Subjects (10 males and 2 females) without histories of opiate dependence were injected in an antecubetal vein with 0, 2.5, 5.0 or 10 mg/70 kg of morphine, by using a...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://pubmed.ncbi.nlm.nih.gov/8301543

データ提供：米国国立医学図書館（NLM）

Unveiling the Hidden Depths of Morphine

Morphine, a potent pain reliever, has been used for centuries to alleviate suffering. This research examines the subjective, psychomotor, and physiological effects of morphine in healthy volunteers. Like a desert explorer venturing into uncharted territory, researchers meticulously investigated the impact of morphine on various aspects of human experience. Their findings revealed a complex interplay between morphine and various bodily functions, providing valuable insights into the drug's effects.

Navigating the Desert of Pain Relief

The study's findings highlight the complex and multifaceted effects of morphine, emphasizing the need for careful monitoring and individualized dosing. It's like navigating a desert landscape, where understanding the terrain and adapting to changing conditions is crucial for a safe journey. This research serves as a reminder of the importance of understanding the full range of a drug's effects to ensure its safe and effective use.

The Desert of Pain

The desert of pain can be a challenging and isolating place. This research offers valuable insights into the use of morphine, helping us understand the drug's effects and optimize its use for pain relief.

Dr.Camel's Conclusion

The research on morphine underscores the importance of understanding the multifaceted effects of this powerful drug. It's like exploring a desert landscape, where recognizing the terrain and navigating with care are essential for a safe journey.

Date :
  1. Date Completed 1994-03-10
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

8301543

DOI: Digital Object Identifier

8301543

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・Effects of morphine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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