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[Oral triple therapy for eradication of Helicobacter pylori in duodenal ulcer disease].
Author: BörschG, GyenesE, LabenzJ, RühlG H
Original Abstract of the Article :
25 patients with Helicobacter pylori-associated active duodenal ulcer disease (bleeding: n = 5, penetrating: n = 1, stenosis of the bulb: n = 4, frequent ulcer relapse: n = 18) were treated with 3 x 600 mg bismuth subsalicylate (BSS), 3 x 400 mg metronidazole and 3 x 500 mg tetracycline in addition ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8326916
データ提供:米国国立医学図書館(NLM)
Triple Therapy for Eradication of Helicobacter pylori in Duodenal Ulcer Disease
This study investigates the efficacy of a triple therapy regimen for eradicating Helicobacter pylori, a bacterium associated with duodenal ulcer disease. The study included 25 patients with active duodenal ulcers, treated with a combination of bismuth subsalicylate, metronidazole, and tetracycline. The results showed that 92% of patients were Helicobacter pylori-negative four weeks after treatment, and 96% of ulcers had healed after six weeks. However, the study also noted a high rate of side effects, including gastrointestinal disturbances, which limited the overall attractiveness of this therapeutic regimen.The Quest for Effective Helicobacter pylori Eradication
This research highlights the ongoing challenge of finding effective and well-tolerated treatments for Helicobacter pylori infection. The high eradication rates achieved in this study are encouraging, but the significant side effects associated with the triple therapy regimen demand further investigation. It's like searching for a safe path through a treacherous desert - finding a solution that effectively eliminates the threat while minimizing the risks.Managing Helicobacter pylori: A Balancing Act
This research underscores the importance of finding a balance between efficacy and tolerability when treating Helicobacter pylori infections. While a triple therapy regimen may offer a high eradication rate, the potential for side effects should be carefully considered. It's a delicate balancing act, much like a camel navigating a narrow path through sand dunes, where the goal is to reach the destination without falling into the treacherous depths.Dr.Camel's Conclusion
This study demonstrates the complex challenges of treating Helicobacter pylori infections. While the triple therapy regimen shows promise, the significant side effects demand further investigation. The search for effective and well-tolerated treatments continues, just as a camel tirelessly traverses the desert in search of a hidden oasis.Date :
- Date Completed 1993-08-09
- Date Revised 2020-12-09
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