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Helicobacter pylori and peptic ulcer disease. Reexamining the therapeutic approach.

Author: FedotinM S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Helicobacter pylori is a major causative factor in peptic ulcer disease. Triple-drug therapy with bismuth and antibiotics is recommended for eradication. Side effects include pseudomembranous colitis and drug resistance.
Paper Details　
Original Abstract of the Article :
Now that Helicobacter pylori has been strongly implicated as a causative factor in peptic ulcer disease, the dictum "no acid--no ulcer" may no longer be valid. However, H pylori has proved difficult to eradicate, and the approach to treatment of peptic ulcer is undergoing changes. At present, a trip...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/8361941

データ提供：米国国立医学図書館（NLM）

Helicobacter pylori and Peptic Ulcer Disease: A Shifting Paradigm

Our understanding of peptic ulcer disease, a chronic condition characterized by sores in the lining of the stomach or duodenum, has undergone a dramatic shift with the discovery of Helicobacter pylori. This research explores the evolving therapeutic approach to peptic ulcer disease, taking into account the role of this ubiquitous bacterium.

The Eradication of Helicobacter pylori: A New Treatment Strategy

The researchers emphasize the importance of eradicating Helicobacter pylori in the treatment of peptic ulcer disease. They recommend a triple-drug combination of bismuth and antibiotics, while also advocating for pre- and post-treatment cultures to monitor the efficacy of the treatment.

A New Era in Peptic Ulcer Disease Management

The study highlights the significant shift in our understanding of peptic ulcer disease. The discovery of Helicobacter pylori as a causative factor has paved the way for new treatment strategies aimed at eradicating this bacterium and improving patient outcomes.

Dr.Camel's Conclusion

This research underscores the pivotal role of Helicobacter pylori in peptic ulcer disease. By shifting the focus from acid reduction to bacterial eradication, the study has ushered in a new era of peptic ulcer disease management, potentially leading to more effective and targeted treatments.
Date :
  1. Date Completed 1993-09-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8361941

DOI: Digital Object Identifier

8361941

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・Side Effects of bismuth subsalicylate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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