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A comparative study of the efficacy, safety and tolerance of azithromycin, dicloxacillin and flucloxacillin in the treatment of children with acute skin and skin-structure infections.

Author: MartinA, MilgramE, ProsperiJ, Pérez-GutiérrezF, Rodriguez-SolaresA

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Azithromycin, a three-day antibiotic regimen, was compared to a seven-day regimen of dicloxacillin or flucloxacillin for treating skin infections in children. Both treatments were found to be equally effective and well-tolerated, with similar rates of clinical response and bacterial eradication. This suggests that azithromycin is an effective and convenient treatment option for skin infections in children.
Paper Details　
Original Abstract of the Article :
An open, randomized, multicentre study was undertaken to compare a three-day regimen of azithromycin with a seven-day course of dicloxacillin or flucloxacillin in the treatment of 118 children (aged 2-12 years) with clinically diagnosed acute skin and skin-structure infections. Sixty patients receiv...See full text at original site
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引用元：
https://doi.org/10.1093/jac/31.suppl_e.103

データ提供：米国国立医学図書館（NLM）

Azithromycin, Dicloxacillin, and Flucloxacillin: A Comparative Study of Antibiotics for Skin Infections

Skin infections are a common concern, particularly in children. This study compares the efficacy and safety of three antibiotics, azithromycin, dicloxacillin, and flucloxacillin, in treating acute skin and skin-structure infections in children.

Effective and Well-Tolerated: Azithromycin Shows Promise for Skin Infections

The study found that azithromycin was as effective and well-tolerated as dicloxacillin and flucloxacillin in treating acute skin and skin-structure infections in children. Both azithromycin and the cloxacillin esters demonstrated high cure and improvement rates, with minimal side effects. This research provides valuable insights into the treatment of skin infections in children, offering healthcare providers a safe and effective option.

Navigating the Landscape of Childhood Infections

This research offers a valuable tool for pediatricians seeking effective treatments for childhood skin infections. The findings provide evidence to support the use of azithromycin as a safe and effective alternative to cloxacillin esters. It's like discovering a new oasis in the desert of childhood ailments, offering a refreshing and reliable source of relief.

Dr. Camel's Conclusion

Skin infections can be a nuisance, especially for our little ones. This research provides a helpful roadmap for pediatricians, showcasing the effectiveness of azithromycin in treating these infections. It's a reminder that medical science is constantly advancing, offering new tools to combat disease and protect the health of our children.
Date :
  1. Date Completed 1993-10-05
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

8396081

DOI: Digital Object Identifier

10.1093/jac/31.suppl_e.103

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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