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Effects of dimenhydrinate on gastric tachyarrhythmia and symptoms of vection-induced motion sickness.

Author: JokerstM, KochK L, MuthE R, SternR M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

Dimenhydrinate reduced motion sickness symptoms by depressing central nervous system activity and possibly by suppressing abnormal gastric myoelectric activity.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Previous research in our laboratory has shown that symptoms of motion sickness are accompanied by the loss of normal 3 cpm activity and the development of tachyarrhythmia in the electrogastrogram (EGG). HYPOTHESIS: We hypothesized that dimenhydrinate would prevent the development of gas...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8588792

データ提供：米国国立医学図書館（NLM）

Dimenhydrinate: A Potential Remedy for the Nausea of Motion Sickness

The desert of [motion sickness] can be a challenging and uncomfortable experience, with symptoms ranging from [nausea] to [vomiting]. This study investigates the effectiveness of [dimenhydrinate], a common anti-nausea medication, in reducing the symptoms of [vection-induced motion sickness]. The authors exposed participants to a rotating optokinetic drum, which induces [vection], and compared the effects of [dimenhydrinate] to [placebo] on [motion sickness symptoms] and [gastric myoelectric activity].

A Suppressive Effect on Motion Sickness Symptoms

The study found that [dimenhydrinate] significantly reduced [motion sickness symptoms] compared to [placebo], as measured by [motion sickness symptom scale (SSMS)] scores. The authors also observed a decrease in [gastric tachyarrhythmia], a common symptom of [motion sickness], in participants who received [dimenhydrinate]. This finding suggests that [dimenhydrinate] may work by suppressing [central nervous system activity] and reducing abnormal [gastric myoelectric activity].

Navigating the Desert of Motion Sickness: A Quest for Relief

This study provides evidence for the effectiveness of [dimenhydrinate] in reducing [motion sickness symptoms]. While [dimenhydrinate] can be a valuable tool for navigating the desert of [motion sickness], it's important to remember that it can cause [drowsiness], and its use should be carefully considered, especially for individuals engaging in activities requiring alertness. Finding the right remedy for [motion sickness] is like discovering a hidden oasis in the desert, providing much-needed relief and restoring comfort.

Dr. Camel's Conclusion

The study's findings suggest that [dimenhydrinate] can be a helpful remedy for [motion sickness] by reducing symptoms and suppressing abnormal gastric activity. As a wise camel, I always recommend using [motion sickness medications] with caution and to seek medical advice if you experience persistent or severe symptoms.

Date :
  1. Date Completed 1996-03-28
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8588792

DOI: Digital Object Identifier

8588792

Related Literature

Article Analysis
・Effects of dimenhydrinate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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