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Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease.

Author: BauditzJ, GaschéC, HowaldtS, LochsH, NikolausS, RaedlerA, SchnoorM, SchreiberS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

In patients with inflammatory bowel disease and anemia refractory to treatment with iron and vitamins, treatment with oral iron and recombinant erythropoietin can raise hemoglobin levels. 12 weeks of therapy with recombinant erythropoietin and oral iron increased mean (+/-SE) hemoglobin concentrations from 8.81+/-0.27 g per deciliter (5.47+/-0.17 micromol per liter) to 10.52+/-0.41 g per deciliter (6.5+/-0.25 micromol per liter), whereas hemoglobin concentrations in the placebo group decreased from 8.69+/-0.11 g per deciliter (5.4+/-0.068 micromol per liter) to 7.84+/- 0.33 g per deciliter (4.9+/-0.2 mmol per liter) (P<0.001).
Paper Details　
Original Abstract of the Article :
BACKGROUND: Some patients with inflammatory bowel disease have anemia that is refractory to treatment with iron and vitamins. We examined whether administering iron and recombinant erythropoietin could raise hemoglobin levels in such patients. METHODS: Thirty-four patients with inflammatory bowel d...See full text at original site
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引用元：
https://doi.org/10.1056/NEJM199603073341002

データ提供：米国国立医学図書館（NLM）

Fighting Anemia in Inflammatory Bowel Disease: A New Hope

Inflammatory bowel disease (IBD) is like a desert storm, raging within the body. It can lead to anemia, leaving the body weak and depleted. This research is like a refreshing oasis, offering a new treatment for IBD-related anemia. The researchers investigated the effectiveness of iron and a drug called erythropoietin (EPO) in raising hemoglobin levels. They found that combining these treatments significantly improved hemoglobin levels, offering hope to patients who struggled with anemia.

EPO: A Powerful Tool in Fighting Anemia

EPO is a hormone that stimulates the production of red blood cells. The research showed that combining EPO with iron therapy effectively increased hemoglobin levels in patients with IBD-related anemia. It's like a desert spring, replenishing the body's resources and restoring strength.

Hope for Patients with IBD

This research offers a beacon of hope for patients suffering from IBD-related anemia. By combining iron and EPO, doctors can effectively treat anemia and improve the quality of life for these patients. Imagine a future where patients with IBD can enjoy the same vitality as others, free from the debilitating effects of anemia.

Dr.Camel's Conclusion

This research is a testament to the power of scientific advancements in addressing complex medical challenges. The combination of iron and EPO offers a promising treatment option for IBD-related anemia, restoring hope and improving the lives of countless patients.
Date :
  1. Date Completed 1996-04-01
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

8592524

DOI: Digital Object Identifier

10.1056/NEJM199603073341002

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・Effective treatment of anemia
SNS
PICO Info
in preparation
Languages

English

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