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Biochemical effects of oral sodium phosphate.

Author: BuckleyS E, CulpepperR M, DiPalmaJ A, WarnerB A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Oral sodium phosphate cleansing was found to cause significant hypocalcemia and hyperphosphatemia in healthy individuals, raising concerns about its use in individuals with cardiopulmonary, renal, or hepatic disease.
Paper Details　
Original Abstract of the Article :
Our objective was to monitor serum and urine biochemical changes after oral sodium phosphate cleansing in a prospectively designed study. The study subjects were seven healthy, asymptomatic adults. Sodium phosphate 45 ml diluted in 45 ml water was given orally at baseline and 12 hr later. Calcium, i...See full text at original site
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引用元：
https://doi.org/10.1007/BF02213131

データ提供：米国国立医学図書館（NLM）

Oral Sodium Phosphate: A Closer Look at its Biochemical Effects

[Oral sodium phosphate] is a commonly used bowel preparation agent, but its biochemical effects have been a subject of debate. This study investigates the changes in serum and urine biochemistry following oral sodium phosphate cleansing in healthy individuals. The researchers found that oral sodium phosphate administration led to significant [hypocalcemia (low calcium levels)] and [hyperphosphatemia (high phosphorus levels)], raising concerns about its potential risks, especially in individuals with underlying medical conditions. The study emphasizes the importance of careful monitoring and considering the potential risks before administering oral sodium phosphate.

A Hidden Dune: The Potential Risks of Oral Sodium Phosphate

The study found that oral sodium phosphate administration led to significant changes in calcium and phosphorus levels in the blood. This is like uncovering a hidden dune in the desert: what appears to be a simple procedure can have unexpected and potentially harmful consequences. The findings suggest that oral sodium phosphate, while effective for bowel preparation, may carry risks for some individuals, particularly those with pre-existing medical conditions.

Navigating the Desert of Bowel Preparation: A Call for Caution

The desert teaches us to be cautious and prepared for unexpected challenges. This study highlights the importance of understanding the potential risks of oral sodium phosphate and carefully considering individual patient factors before administering this bowel preparation agent. By taking a cautious approach, healthcare providers can help ensure the safety and well-being of their patients.

Dr.Camel's Conclusion

This study highlights the significant biochemical effects of oral sodium phosphate, underscoring the importance of careful monitoring and considering the potential risks before administering this bowel preparation agent.

Date :
  1. Date Completed 1996-08-15
  2. Date Revised 2022-03-09
Further Info :

Pubmed ID

8674396

DOI: Digital Object Identifier

10.1007/BF02213131

Related Literature

Article Analysis
・Effects of sodium phosphate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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