Deficient nitric oxide responsible for reduced nerve blood flow in diabetic rats: effects of L-NAME, L-arginine, sodium nitroprusside and evening primrose oil.

Author: DewhurstM, MahmoodS, OmawariN, StevensE, TomlinsonD R, VoP

Paper Details 
Original Abstract of the Article :
1. This study examined the potential role of impaired nitric oxide production and response in the development of endoneurial ischaemia in experimental diabetes. Rats were anaesthetized (Na pentobarbitone 45 mg kg-1, diazepam 2 mg kg-1) for measurement of sciatic nerve laser Doppler flux and systemic...See full text at original site
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引用元:
https://doi.org/10.1111/j.1476-5381.1996.tb15384.x

データ提供:米国国立医学図書館(NLM)

Nitric Oxide Deficiency: A Key Player in Diabetic Nerve Damage

This study delves into the complex world of diabetes and its impact on nerve health. It's like a desert expedition, where researchers are exploring the mechanisms behind diabetic nerve damage. The study focuses on the role of nitric oxide (NO), a molecule that plays a vital role in regulating blood flow. The research suggests that a deficiency in NO production contributes to the development of endoneurial ischaemia, a condition that restricts blood flow to nerves, in diabetic rats. The researchers investigated the effects of various NO-related compounds on nerve blood flow, finding that L-arginine and sodium nitroprusside could improve blood flow in diabetic rats.

Nitric Oxide: A Vital Component of Nerve Health

This research highlights the importance of nitric oxide (NO) in maintaining nerve health, especially in the context of diabetes. It's like a desert well, providing a vital source of nourishment to sustain the delicate network of nerves. The study's findings suggest that promoting NO production could be a promising strategy for preventing or treating diabetic nerve damage.

Protecting Your Nerves: A Desert Oasis of Knowledge

This study serves as a reminder of the importance of maintaining good nerve health, especially for individuals with diabetes. It's like a desert oasis, offering a haven of knowledge about the delicate balance of nerve function. The study's findings encourage us to explore ways to promote NO production and protect our nerves from the damaging effects of diabetes.

Dr.Camel's Conclusion

This study takes us deep into the desert of diabetes, revealing the vital role of nitric oxide in maintaining nerve health. It's like a desert explorer's journey, where researchers are uncovering the secrets of this complex condition. The findings underscore the importance of addressing NO deficiency in diabetic patients to protect their nerves and prevent further damage. It's a journey of understanding that could lead to new strategies for managing diabetes and improving the quality of life for those affected.

Date :
  1. Date Completed 1996-10-10
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

8733594

DOI: Digital Object Identifier

10.1111/j.1476-5381.1996.tb15384.x

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Languages

English

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