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High bone turnover is associated with low bone mass and spinal fracture in postmenopausal women.

Author: AndreassenH, BidstrupM, ClemmesenB, GunnesM, RavnP, RixM

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

This study found a strong association between high bone turnover, low bone mass, and prevalence of spinal fracture in postmenopausal women. These results support the theory that high bone turnover is a risk factor for osteoporosis and spinal fracture.
Paper Details　
Original Abstract of the Article :
A group of 366 healthy, white postmenopausal women, aged 50-81 years, mean age 66 years, were selected from the screened population of Scandinavians who were part of a multicenter study of the efficacy of tiludronate, a new bisphosphonate, in established postmenopausal osteoporosis. Eighty-eight wom...See full text at original site
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引用元：
https://doi.org/10.1007/s002239900225

データ提供：米国国立医学図書館（NLM）

Bone Turnover: A Key to Understanding Osteoporosis in Postmenopausal Women

Osteoporosis, a condition characterized by weakened bones, is like a fragile desert landscape vulnerable to erosion and collapse. This study investigates the role of bone turnover, the process of bone breakdown and renewal, in postmenopausal women, seeking to understand how this process contributes to osteoporosis and fracture risk. The researchers, like skilled desert archaeologists, examined bone turnover markers in a group of postmenopausal women, seeking to uncover the secrets behind bone health.

Unveiling the Secrets of Bone Turnover

The study found a strong association between high bone turnover, low bone mass, and an increased risk of spinal fracture in postmenopausal women. This suggests that high bone turnover may be a significant risk factor for osteoporosis and bone fragility.

Implications for Osteoporosis Prevention and Management

These findings highlight the importance of monitoring bone turnover in postmenopausal women to identify those at higher risk for osteoporosis.

Dr.Camel's Conclusion

This study offers crucial insights into the role of bone turnover in osteoporosis. It emphasizes the importance of maintaining a healthy balance in bone metabolism and suggests that interventions aimed at reducing excessive bone turnover could play a vital role in preventing osteoporosis and fractures.

Date :
  1. Date Completed 1997-05-29
  2. Date Revised 2019-08-31
Further Info :

Pubmed ID

9069162

DOI: Digital Object Identifier

10.1007/s002239900225

Related Literature

Article Analysis
・Effects of tiludronate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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