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Effects of anesthetic technique on side effects associated with fentanyl Oralet premedication.

Author: GreenW, HuntingtonJ, MalviyaS, SiewertM, Voepel-LewisT

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

Oral transmucosal fentanyl citrate (OTFC) was effective in producing sedation and facilitating cooperation with induction, but was associated with significant postoperative nausea and vomiting (PONV).
Paper Details　
Original Abstract of the Article :
STUDY OBJECTIVES: To evaluate the efficacy of 5 to 10 micrograms/kg of oral transmucosal fentanyl citrate (OTFC) as an anesthetic premedication, and to determine whether propofol induction reduces postoperative nausea and vomiting (PONV) in pediatric patients premedicated with OTFC undergoing outpat...See full text at original site
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引用元：
https://doi.org/10.1016/s0952-8180(97)00064-0

データ提供：米国国立医学図書館（NLM）

Fentanyl Oralet: Exploring Its Use as an Anesthetic Premedication

Oral transmucosal fentanyl citrate (OTFC) is a premedication option for children undergoing surgery. This study, a randomized, double-blinded trial, evaluated the efficacy and side effects of OTFC as an anesthetic premedication in pediatric patients. The researchers found that OTFC effectively produced sedation and facilitated cooperation with induction, but it was associated with a significant incidence of postoperative nausea and vomiting (PONV). This study highlights the need for careful consideration of the potential benefits and risks associated with OTFC premedication.

Fentanyl Oralet: Weighing the Benefits and Risks

The study's findings suggest that OTFC can be a valuable tool for facilitating anesthetic procedures in children, but its use requires careful consideration of the potential for PONV. Clinicians must weigh the benefits of sedation and cooperation with the risk of adverse effects. This research encourages further investigation into strategies to minimize the incidence of PONV and optimize the use of OTFC as a safe and effective premedication option.

Managing Anesthesia in Children: Navigating the Challenges

Providing anesthesia to children is a delicate balancing act, like navigating a desert landscape with its own unique challenges. This study highlights the importance of considering the potential side effects of premedication and the need for individualized approaches to anesthesia management in children. By carefully assessing the risks and benefits of various medications and techniques, healthcare providers can strive to ensure a safe and comfortable experience for young patients.

Dr. Camel's Conclusion

The world of pediatric anesthesia is a delicate dance, requiring expertise, compassion, and a careful understanding of the unique needs of young patients. This study, like a camel caravan traversing a desert of uncertainties, offers valuable insights into the use of fentanyl Oralet as a premedication option. While it highlights potential benefits, it also reminds us that navigating the complexities of anesthesia requires a cautious and thoughtful approach, ensuring the safety and well-being of our youngest patients.
Date :
  1. Date Completed 1997-10-30
  2. Date Revised 2019-09-14
Further Info :

Pubmed ID

9257202

DOI: Digital Object Identifier

10.1016/s0952-8180(97)00064-0

Related Literature

Article Analysis
・Side Effects of fentanyl
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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