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Side effects of chemotherapy for advanced urothelial carcinoma with etoposide and ifosfamide.

Author: GoesslC, HeicappellR, MillerK, MüllerM, SteinerU

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigates the use of combination chemotherapy with etoposide and ifosfamide for advanced urothelial carcinoma. This regimen has shown comparable therapeutic effectiveness to previous cisplatin-based regimens, but with fewer nephrotoxic side effects.
Paper Details　
Original Abstract of the Article :
To date, chemotherapy for advanced urothelial carcinoma has been associated with only moderate therapeutic success and minimal extension of survival. This, coupled with the occurrence of serious side effects and the resulting reduced quality of life, underscores the need for new chemotherapeutic age...See full text at original site
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引用元：
https://doi.org/10.1159/000283073

データ提供：米国国立医学図書館（NLM）

Navigating the Side Effects of Chemotherapy for Advanced Urothelial Carcinoma

Advanced urothelial carcinoma, a type of bladder cancer, presents a significant challenge for patients and healthcare providers. This study examines the side effects of chemotherapy using etoposide and ifosfamide, a common treatment regimen for advanced urothelial carcinoma. The researchers sought to understand the potential toxicity associated with this chemotherapy combination, aiming to improve patient care by minimizing adverse effects. The study delves into the complexities of cancer treatment, highlighting the importance of balancing therapeutic efficacy with patient well-being.

Etoposide and Ifosfamide: Balancing Efficacy and Toxicity

The study found that the chemotherapy combination of etoposide and ifosfamide, while offering comparable therapeutic effectiveness to traditional regimens, was associated with a reduction in nephrotoxic side effects. This finding suggests that this chemotherapy regimen could offer a less toxic option for patients with advanced urothelial carcinoma and compromised renal function.

A More Tolerable Approach to Cancer Treatment

This study emphasizes the importance of considering individual patient factors, including renal function, when selecting chemotherapy regimens. The researchers' findings highlight the potential of etoposide and ifosfamide to offer a more tolerable treatment option for patients with advanced urothelial carcinoma.

Dr.Camel's Conclusion

This study underscores the importance of ongoing research to develop more effective and less toxic treatment options for cancer patients. The findings provide a glimpse into the potential of new chemotherapy regimens to improve patient care and minimize side effects.

Date :
  1. Date Completed 1998-02-27
  2. Date Revised 2018-02-17
Further Info :

Pubmed ID

9444744

DOI: Digital Object Identifier

10.1159/000283073

Related Literature

Article Analysis
・Side Effects of etoposide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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