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Timing and side effects of flumazenil for dental outpatients receiving intravenous sedation with midazolam.

Author: KunimatuT, KyodaN, MisakiT, OkaS, TajimaA, TakadaK

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Flumazenil, an antidote for benzodiazepine overdose, should be given at least 60 minutes after intravenous sedation with midazolam in dental outpatients to avoid resedation and side effects.
Paper Details　
Original Abstract of the Article :
We studied the timing and side effects of flumazenil treatment for 10 healthy volunteers and 46 dental outpatients who received intravenous sedation with midazolam. For the volunteers, vital signs were monitored before and after intravenous injection of midazolam and flumazenil. In addition, grip st...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148936/

データ提供：米国国立医学図書館（NLM）

Flumazenil: A Guide to Reversing Sedation in Dental Outpatients

In the world of dentistry, sedation is often used to help patients feel comfortable during procedures. But what happens when a patient needs to wake up quickly? This research explores the timing and side effects of using flumazenil, a medication used to reverse the effects of midazolam, a common sedative used in dentistry. It's like navigating a desert oasis - knowing when to leave and how to safely make your way back to reality.

Timing is Key

The research found that flumazenil should be given at least 60 minutes after midazolam sedation. It's like giving the desert traveler enough time to adjust to the desert environment before venturing back out. The study also revealed that while flumazenil was generally safe and effective, there were some potential side effects, such as excitability and nausea.

A Careful Journey

This research provides important information for dentists and patients, highlighting the importance of careful timing and understanding potential side effects when using flumazenil. It's like knowing the best time to leave the oasis and the risks involved in the journey back across the desert.

Dr.Camel's Conclusion

This study is a valuable resource for dental professionals and patients, emphasizing the importance of safe and effective sedation management. It's like having a reliable guidebook for navigating the desert, ensuring a safe and comfortable journey.
Date :
  1. Date Completed 1998-03-31
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

9481956

DOI: Digital Object Identifier

PMC2148936

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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