A single-blind, crossover comparison of the pharmacokinetics and cognitive effects of a new diazepam rectal gel with intravenous diazepam.

Author: BeniakT E, CloydJ C, LalondeR L, NovackG D

Paper Details 
Original Abstract of the Article :
PURPOSE: The objective of this study was to compare the pharmacokinetics and cognitive effects of a new diazepam (DZP) rectal gel (Diastat) with intravenously administered DZP. METHODS: Twenty healthy volunteers were enrolled in a single-blind, randomized, double-dummy, two-period, crossover study....See full text at original site
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引用元:
https://doi.org/10.1111/j.1528-1157.1998.tb01415.x

データ提供:米国国立医学図書館(NLM)

Diazepam Rectal Gel: A New and Effective Route for Anxiety Relief

This research compares the effectiveness of a new diazepam rectal gel with intravenous diazepam for treating anxiety. Imagine anxiety as a scorching desert sun, causing you to feel overwhelmed and uneasy. Diazepam is a medication that can provide relief from anxiety, but traditional methods of administration, such as intravenous injection, can be inconvenient. This study explores a new rectal gel formulation of diazepam, offering a potentially easier and more comfortable way to administer the medication. The researchers conducted a single-blind, crossover study, comparing the pharmacokinetics (how the body absorbs and processes the drug) and cognitive effects of the rectal gel with intravenous diazepam. The findings suggest that the rectal gel provides rapid and consistent absorption of diazepam, similar to intravenous administration, while producing minimal cognitive side effects. This study offers promising evidence for the use of rectal diazepam gel as a safe and effective alternative to intravenous administration, potentially improving patient comfort and convenience.

Diazepam Rectal Gel: A New Frontier in Anxiety Treatment

This research highlights the potential of diazepam rectal gel as a safe and effective alternative to intravenous administration for treating anxiety. The findings offer a new and potentially more comfortable way to administer diazepam, potentially improving patient experience and convenience.

Navigating Anxiety: Finding the Right Treatment

Anxiety is a common condition that can have a significant impact on quality of life. This study encourages exploring different treatment options, including new and innovative approaches, to find the best fit for individual needs and preferences.

Dr.Camel's Conclusion

This study, like a cool desert breeze, offers a refreshing approach to anxiety treatment. The researchers are exploring new and innovative ways to administer diazepam, potentially enhancing patient comfort and convenience. This research is a testament to the ongoing quest for more effective and patient-centered treatment approaches.

Date :
  1. Date Completed 1998-06-02
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

9596205

DOI: Digital Object Identifier

10.1111/j.1528-1157.1998.tb01415.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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