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Bicalutamide in advanced prostate cancer. A review.

Author: GoaK L, SpencerC M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Bicalutamide, a nonsteroidal antiandrogen, offers a once-daily administration schedule and is well-tolerated with fewer side effects than flutamide.
Paper Details　
Original Abstract of the Article :
Bicalutamide is a nonsteroidal antiandrogen with a long elimination half-life (t1/2) that permits once-daily administration. When combined with a gonadorelin (gonadotrophin releasing hormone; GnRH) agonist in maximum androgen blockade (MAB) regimens, bicalutamide 50 mg once daily is at least as effe...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.2165/00002512-199812050-00006

データ提供：米国国立医学図書館（NLM）

Echinococcus granulosus: A Worm with a Trick Up its Sleeve

Echinococcus granulosus is a type of parasitic tapeworm that can cause hydatid disease, a serious infection that affects the liver, lungs, and other organs. It's like a pesky desert sandfly, constantly buzzing around and causing irritation. This study investigates the effects of anti-hydatidosis drugs, such as mebendazole, albendazole, and praziquantel, on the biochemical activity of E. granulosus cysts.

The researchers found that these drugs effectively suppressed the activity of malate dehydrogenase (MD), an enzyme involved in the metabolism of the cyst wall. This suggests that MD may be a potential target for anti-hydatidosis drugs.

New Insights into Echinococcus granulosus: A Step Towards Better Treatment

This study provides valuable insights into the biochemical mechanisms of E. granulosus, potentially leading to the development of more effective anti-hydatidosis treatments.

Living with Hydatid Disease: Seeking the Right Path

Hydatid disease can be a serious condition, but early diagnosis and treatment are crucial. It's important to consult with a healthcare professional who specializes in parasitic infections to develop a personalized treatment plan.

Dr. Camel's Conclusion

Echinococcus granulosus is a tenacious parasite, but researchers are constantly striving to develop new strategies for tackling this desert nomad.

Date :
  1. Date Completed 1998-07-17
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

9606617

DOI: Digital Object Identifier

10.2165/00002512-199812050-00006

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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