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An endoscopic comparison of gastroduodenal injury with over-the-counter doses of ketoprofen and acetaminophen.

Author: CodispotiJ R, LanzaF L, NelsonE B

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study endoscopically assessed the gastrointestinal effects of over-the-counter (OTC) doses of ketoprofen in healthy subjects. Ketoprofen is a potent NSAID recently approved for OTC use. The gastrointestinal effects of the OTC dose of ketoprofen were investigated.
Paper Details　
Original Abstract of the Article :
The objective of this study was to endoscopically assess in healthy subjects the gastrointestinal effects of over-the-counter (OTC) doses of ketoprofen. Ketoprofen is a potent nonsteroidal antiinflammatory agent (NSAID) recently approved for OTC use as an analgesic/antipyretic at doses of 75 mg vers...See full text at original site
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引用元：
https://doi.org/10.1111/j.1572-0241.1998.00327.x

データ提供：米国国立医学図書館（NLM）

Endoscopic Assessment of Gastroduodenal Injury from OTC Ketoprofen

This study takes a close look at the potential gastrointestinal effects of over-the-counter (OTC) ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief. NSAID use is known to be associated with gastrointestinal side effects, and ketoprofen has been particularly linked to higher risks of complications. Researchers aimed to assess the impact of OTC doses of ketoprofen on the stomach and duodenum using endoscopic examinations. The study's findings could provide valuable information for healthcare professionals and consumers regarding the safe and effective use of OTC ketoprofen.

OTC Ketoprofen: Potential Gastrointestinal Risks

The study's results suggest that even OTC doses of ketoprofen may have the potential to cause gastrointestinal injury. While the study was conducted on healthy individuals, it highlights the need for caution when using NSAIDs, even at lower doses. Patients with pre-existing gastrointestinal conditions should be particularly vigilant and consult with their healthcare providers before using OTC ketoprofen.

NSAID Use: A Balance of Benefits and Risks

NSAID use is a common practice for pain relief, but it's important to remember that they are not without risks. This study underscores the importance of weighing the benefits of NSAID use against the potential risks, especially gastrointestinal complications. Consulting with a healthcare professional is key to ensuring safe and effective use of OTC medications.

Dr.Camel's Conclusion

This research is like a reminder to be mindful of even seemingly innocuous OTC medications. Like navigating a desert, where even a small misstep can lead to trouble, it's important to understand the potential risks associated with NSAIDs. This study serves as a valuable reminder to use OTC medications responsibly and consult with your healthcare provider if you have any concerns.

Date :
  1. Date Completed 1998-07-31
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

9672328

DOI: Digital Object Identifier

10.1111/j.1572-0241.1998.00327.x

SNS
PICO Info
in preparation
Languages

English

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