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Tazarotene 0.1% gel plus corticosteroid cream in the treatment of plaque psoriasis.

Author: BrenemanD L, GibsonJ R, GoffeB S, GrossmanJ R, LebwohlM G, Lew-KayaD A, LingM R, LueJ C, MilbauerJ, PincusS H, SeftonJ, SibbaldR G, SwinyerL J, WeinsteinG D

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study discusses the use of topical corticosteroids and tazarotene, a retinoid, in treating psoriasis. Topical corticosteroids are frequently used but can lead to serious side effects with long-term use. Tazarotene has shown significant clinical benefits but can cause mild to moderate irritation.
Paper Details　
Original Abstract of the Article :
Topical corticosteroids are often used in the treatment of psoriasis, but long-term use may be associated with serious adverse events such as tachyphylaxis or atrophy of the skin. Tazarotene, a new topical retinoid, has demonstrated significant clinical benefits but can cause mild to moderate local ...See full text at original site
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引用元：
https://doi.org/10.1016/s0190-9622(98)70008-8

データ提供：米国国立医学図書館（NLM）

Psoriasis: A New Alliance for Treatment

The field of [psoriasis treatment] is continually searching for effective and well-tolerated therapies to manage this chronic skin condition. This study explores the potential of combining [tazarotene 0.1% gel] and [corticosteroid cream] in treating [plaque psoriasis]. The authors investigated the efficacy of this combination therapy, seeking to leverage the strengths of both treatments while minimizing potential side effects.

A Combined Approach: Tazarotene and Corticosteroids

The study explores the potential benefits of combining tazarotene, a topical retinoid, with corticosteroid cream in treating plaque psoriasis. The authors aimed to harness the synergistic effects of these two treatments, potentially leading to enhanced efficacy and improved patient outcomes. The findings could offer a new and effective approach to managing plaque psoriasis, providing patients with a broader range of treatment options.

Navigating the Challenges of Psoriasis: A New Pathway

This research highlights the ongoing search for effective and well-tolerated treatments for psoriasis. The study's findings could pave the way for new therapeutic strategies, offering patients a wider range of options for managing this chronic skin condition.

Dr. Camel's Conclusion

Like a camel navigating a rugged desert terrain, researchers are constantly seeking new pathways to address the challenges of psoriasis. This study explores the potential of combining tazarotene and corticosteroids, offering a promising new avenue for managing this chronic skin condition.

Date :
  1. Date Completed 1998-11-04
  2. Date Revised 2019-07-09
Further Info :

Pubmed ID

9777766

DOI: Digital Object Identifier

10.1016/s0190-9622(98)70008-8

Related Literature

Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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