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Toxicity management in patients receiving low-dose aldesleukin therapy.

Author: SundinD J, WolinM J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Low-dose aldesleukin therapy can be administered intravenously or subcutaneously, with adverse events being dependent upon dose, route, and administration schedule. Most adverse reactions are self-limiting and can be managed on an outpatient basis with agents such as antiemetics, antipyretics, and topical creams.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To review the pathophysiology and subsequent treatment options for low-dose aldesleukin-induced toxicity when administered via intravenous bolus infusion, continuous intravenous infusion, or subcutaneous injection. BACKGROUND: The adverse events associated with high-dose aldesleukin ther...See full text at original site
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引用元：
https://doi.org/10.1345/aph.18019

データ提供：米国国立医学図書館（NLM）

Navigating the Side Effects of Aldesleukin Therapy: A Guide for Clinicians

This review article provides a comprehensive guide for managing the toxicities associated with low-dose aldesleukin therapy, a treatment used for various cancers. The authors delve into the complex mechanisms behind aldesleukin-induced toxicity, highlighting the unique challenges associated with this type of immunotherapy. They offer practical advice for clinicians on managing various adverse events, emphasizing the importance of proactive and aggressive treatment strategies. This review serves as a valuable resource for clinicians treating patients with aldesleukin therapy.

A Guide to the Desert: Managing Aldesleukin Therapy Toxicity

This review provides essential guidance for clinicians on managing the side effects of aldesleukin therapy. The authors' thorough analysis and practical recommendations can help ensure that patients receiving this treatment experience minimal discomfort and achieve optimal therapeutic outcomes.

A Balancing Act: Managing Treatment Benefits and Side Effects

This review highlights the importance of balancing the potential benefits of aldesleukin therapy with the risks of its side effects. As Dr. Camel, I'm reminded that even in the harsh desert environment, there are often oases of hope and renewal. Likewise, with careful management, aldesleukin therapy can offer a path to healing, while minimizing the burden of side effects.

Dr.Camel's Conclusion

This review provides a valuable resource for clinicians treating patients with low-dose aldesleukin therapy. By understanding the mechanisms behind toxicity and implementing proactive management strategies, clinicians can help patients navigate the challenges of treatment and achieve optimal therapeutic outcomes.

Date :
  1. Date Completed 1999-03-17
  2. Date Revised 2017-02-14
Further Info :

Pubmed ID

9876817

DOI: Digital Object Identifier

10.1345/aph.18019

Related Literature

Article Analysis
・Side Effects of aldesleukin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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