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[Comparative study of the effects of auranofin and aurothiomalate on laboratory and clinical indicators in patients with rheumatoid arthritis].

Author: StambukB, VlakT

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Auranofin (oral) and aurothiomalate (intramuscular) showed similar effects and tolerability in patients with rheumatoid arthritis. Both treatments significantly improved disease parameters, but aurothiomalate was better tolerated.
Paper Details　
Original Abstract of the Article :
Is there any significant difference in the effect and tolerance of the gold salts applied peroral and intramuscular in patients with rheumatoid arthritis (RA)? 97 patients with RA have been included in the research. Group used auranofin perorally comprised 30 patients with RA, 25 women and 5 men. Th...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/9921004

データ提供：米国国立医学図書館（NLM）

Gold Salts: A Comparative Study in Rheumatoid Arthritis

This research compares the effectiveness and tolerability of two gold salts used to treat rheumatoid arthritis (RA), a chronic autoimmune disease. It's like a gold-mining expedition, exploring the benefits and drawbacks of different gold treatments. The authors compared the effects of oral auranofin and intramuscular aurothiomalate on various clinical and laboratory indicators in patients with RA. It's like comparing two different gold nuggets, assessing their properties and potential value for treating RA.

Gold Standard for Rheumatoid Arthritis?

The study found that both auranofin and aurothiomalate were effective in reducing the severity of RA symptoms, but aurothiomalate was better tolerated than auranofin. It's like finding a treasure map, where one path leads to a hidden gem, but the other may be more treacherous to navigate. The researchers suggest that aurothiomalate might be a more suitable treatment option for patients with RA, based on its better tolerability.

Finding the Right Treatment for Rheumatoid Arthritis

This study provides valuable information for clinicians treating patients with RA. It's like a camel caravan, equipped with a compass and a map to guide them to the best treatment options. By understanding the different treatment options and their potential risks and benefits, healthcare providers can personalize their approach to patient care and optimize outcomes.

Dr.Camel's Conclusion

This research provides valuable insight into the effectiveness and tolerability of gold salts in treating RA. It's a reminder that the search for the best treatment for RA is an ongoing journey, just like a camel's journey across the vast desert. By understanding the different treatment options and their potential risks and benefits, we can work towards finding the most effective and safe therapies for RA patients.

Date :
  1. Date Completed 1999-02-25
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

9921004

DOI: Digital Object Identifier

9921004

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・Side Effects of auranofin
SNS
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in preparation
Languages

Croatian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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