[Effectiveness of ftorafur and hexamethylmelamine in advanced breast cancer].

Author: AsserkritovaI V, GarinA M, LichinitserM R, PerevodchikovaN I, VaarikG Kh

Paper Details 
Original Abstract of the Article :
In 7 oncological institutions of the Soviet Union a correlation was made between the efficacy of fluorofur, hexamethylmelanin and their combination for advanced cancer of the mammary gland in 136 patients. The therapeutic effect was estimated in 104 patients. Fluorofur yielded a considerable tumor r...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/99870

データ提供:米国国立医学図書館(NLM)

Combatting Advanced Breast Cancer: A Tale of Two Drugs

The vast desert of breast cancer research continues to yield new insights. This study explores the effectiveness of two different drugs, fluorofur and hexamethylmelanin, in treating advanced breast cancer. The researchers investigated the efficacy of these drugs individually and in combination in 136 patients across seven oncological institutions in the Soviet Union. The results showed that fluorofur induced tumor regression in 40% of the patients, while hexamethylmelanin achieved a therapeutic effect in 48%. However, the combination of these drugs showed a significantly lower therapeutic effect, suggesting that their combined use may not be beneficial. The study also found that fluorofur was generally better tolerated than hexamethylmelanin, with fewer side effects.

Two Paths Through the Desert of Cancer Treatment

The findings highlight the importance of carefully considering individual patient characteristics and treatment options when treating advanced breast cancer. While fluorofur and hexamethylmelanin showed promise as individual agents, the combination of these drugs did not demonstrate a synergistic effect. This emphasizes the need for a personalized approach to treatment, taking into account factors such as tumor characteristics, patient health, and potential side effects.

Navigating the Shifting Sands of Breast Cancer Treatment

The study sheds light on the complex nature of breast cancer and the ongoing search for effective treatments. While these drugs offer potential therapeutic benefits, further research is needed to optimize their use and develop new treatment approaches. Remember, early detection and personalized treatment are crucial for successful outcomes in the fight against breast cancer.

Dr.Camel's Conclusion

This research underscores the importance of personalized cancer treatment. The study's findings highlight the fact that not all treatments are created equal, and what works for one patient may not work for another. The ongoing search for effective and targeted cancer treatments continues, and this research provides valuable insights into potential avenues for future investigation.

Date :
  1. Date Completed 1978-11-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

99870

DOI: Digital Object Identifier

99870

Related Literature

SNS
PICO Info
in preparation
Languages

Russian

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