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Factors affecting growth and strategies for treatment in children after renal transplantation.
Author: MehlsO, TönshoffB
Original Abstract of the Article :
Growth failure is a frequent side effect of long-term high-dose glucocorticoid therapy in children. Pharmacological doses of glucocorticoids interfere at different levels with the integrity of the somatotropic hormone axis. The majority of patients on chronic corticosteroid medication present with o...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/10084778
データ提供:米国国立医学図書館(NLM)
Growth Challenges After Renal Transplantation in Children: Finding Solutions in the Desert of Immunosuppression
Renal transplantation, a life-saving procedure for children with kidney failure, is like a delicate desert oasis—providing life-sustaining resources. However, this research, like an explorer navigating a challenging landscape, investigates the potential complications associated with long-term immunosuppression, particularly the impact on growth in children. Long-term immunosuppressant therapy, necessary to prevent graft rejection, can sometimes impede growth, much like a desert drought can stunt the growth of plants. The authors explore the challenges of managing growth failure in children who have undergone renal transplantation, focusing on the role of high-dose glucocorticoids, a common component of immunosuppressive regimens.
Addressing Growth Failure: A Multi-faceted Approach
The research highlights the need for a multi-faceted approach to manage growth failure in children post-renal transplantation. Imagine a skilled desert traveler employing various strategies—water conservation, shade seeking, and finding food sources—to survive a challenging journey. Similarly, managing growth failure requires a combination of approaches, such as reducing glucocorticoid doses, exploring alternative medications, and considering growth hormone therapy.
The Importance of Personalized Care
This research underscores the importance of personalized care for children post-renal transplantation. It's like understanding the unique needs of different desert plants—each requires a tailored approach to thrive. The authors emphasize the need to carefully monitor growth, adjust medication regimens as needed, and consider growth hormone therapy when appropriate.
Dr.Camel's Conclusion
This research explores the challenges of managing growth failure in children who have undergone renal transplantation. The authors highlight the need for a personalized and multi-faceted approach, similar to a skilled traveler navigating a challenging desert landscape. Understanding the complex interplay between immunosuppressive medication, growth, and development is crucial for providing optimal care for these children, ensuring their well-being and fostering their growth.
Date :
- Date Completed 1999-04-13
- Date Revised 2012-11-15
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English
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