Azelastine eye drops reduce conjunctival hyperresponsiveness to hyperosmolar glucose challenge in children with asymptomatic mite conjunctivitis.

Author: CanonicaG W, CatrulloA, CerquetiP, CiprandiG, MondinoC, PassalacquaG, ToscaM

Paper Details 
Original Abstract of the Article :
Mite allergy is characterized by a continuous allergen exposure. Persistent inflammation is therefore always detectable; and during symptomless periods as well. It has been reported that mite allergic patients also present a nonspecific hyperreactivity to different stimuli, including hyperosmolar so...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/10212855

データ提供:米国国立医学図書館(NLM)

Azelastine Eye Drops: A Potential Solution for Conjunctival Hyperreactivity in Mite Allergy

Allergy to dust mites, those tiny creatures that reside in our homes, is a common problem. Dust mite allergy is characterized by continuous allergen exposure, leading to persistent inflammation even during seemingly symptom-free periods. These patients often exhibit a nonspecific hyperreactivity to various stimuli, including hyperosmolar solutions. This study delves into the effects of azelastine eye drops, a drug known to reduce allergic inflammation, on this nonspecific conjunctival hyperreactivity in mite-allergic patients. The researchers employed a hyperosmolar conjunctival challenge before and after two weeks of treatment with azelastine eye drops or placebo in 20 children with mite allergy. The results revealed a significant reduction in nonspecific conjunctival hyperreactivity in the azelastine group compared to the placebo group (p = 0.018). This finding suggests that azelastine eye drops effectively alleviate the nonspecific hyperreactivity present in individuals with dust mite allergy.

Azelastine: A Potential Relief for Conjunctival Hyperreactivity

The study's findings are promising and highlight the potential benefits of azelastine eye drops in managing conjunctival hyperreactivity associated with mite allergy. The significant difference in hyperreactivity between the treatment group and the placebo group underscores the effectiveness of azelastine. This could lead to improved symptom management and better quality of life for individuals struggling with dust mite allergies.

Azelastine: A Glimpse of Hope for Dust Mite Allergy Sufferers

This research provides valuable insights into the potential of azelastine in addressing conjunctival hyperreactivity in individuals with dust mite allergy. The results suggest that azelastine may offer relief from the bothersome symptoms associated with this condition. While further studies are needed to confirm these findings and explore long-term effects, this research provides a glimmer of hope for those grappling with dust mite allergy.

Dr.Camel's Conclusion

This research, like a desert oasis, offers a refreshing solution for those suffering from the itchy and watery eyes caused by dust mite allergy. Azelastine eye drops seem to be a promising treatment option for reducing the nonspecific hyperreactivity associated with dust mite allergy. The study's findings, like a shimmering mirage in the desert, point to a potential path to relief for many individuals struggling with this common allergy.

Date :
  1. Date Completed 1999-05-06
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

10212855

DOI: Digital Object Identifier

10212855

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SNS
PICO Info
in preparation
Languages

English

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