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Antifibrinolytic therapy with tranexamic acid in cardiac operations.

Author: HaraguchiN, MatsuiK, MatsuzakiK, NaganoI, TanoueY, TatewakiH

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Tranexamic acid is a medication that can help prevent excessive bleeding after cardiac surgery. Continuous infusion of tranexamic acid with a bolus infusion at the beginning of cardiopulmonary bypass was found to be the most effective regimen in reducing postoperative blood loss.
Paper Details　
Original Abstract of the Article :
To demonstrate its antifibrinolytic effects and establish an effective regimen of tranexamic acid for hemostasis, the authors measured alpha2-plasmin inhibitor-plasmin complexes, thrombin-antithrombin III complexes and postoperative blood loss in three groups undergoing different regimens during car...See full text at original site
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引用元：
https://doi.org/10.1016/s0967-2109(98)00141-0

データ提供：米国国立医学図書館（NLM）

Tranexamic Acid: A Remedy for Blood Loss in Cardiac Operations

This study explores the use of tranexamic acid, a medication that helps stop bleeding, in cardiac operations. Imagine a desert with a raging sandstorm, where the wind whips up dust and debris, creating a chaotic environment. Tranexamic acid acts like a powerful desert oasis, providing relief from the chaos of excessive bleeding during cardiac surgery. This study examines the effectiveness of tranexamic acid in reducing blood loss and improving hemostasis, the process of stopping bleeding, in patients undergoing cardiac surgery.

Tranexamic Acid: A Lifeline in Cardiac Surgery

This research demonstrates the effectiveness of tranexamic acid in controlling blood loss during cardiac operations. The study found that continuous infusion of tranexamic acid, combined with a bolus dose, was the most effective regimen in reducing blood loss and promoting hemostasis. This is like using a well-placed oasis to replenish the body's reserves of water and energy, allowing it to recover from the challenging journey through a desert of surgery.

Minimizing Blood Loss

This research highlights the potential benefits of tranexamic acid in cardiac surgery. By reducing blood loss, tranexamic acid can improve patient outcomes and reduce the risk of complications. It's like finding a source of water in a parched desert, providing essential support for survival and recovery.

Dr. Camel's Conclusion

This research highlights the potential benefits of tranexamic acid in cardiac surgery. By reducing blood loss and improving hemostasis, tranexamic acid can improve patient outcomes and reduce the risk of complications. Just as a desert oasis provides respite from the harsh environment, tranexamic acid provides a lifeline for patients undergoing cardiac surgery, helping them navigate the challenging journey to recovery.

Date :
  1. Date Completed 1999-07-08
  2. Date Revised 2019-10-24
Further Info :

Pubmed ID

10353670

DOI: Digital Object Identifier

10.1016/s0967-2109(98)00141-0

SNS
PICO Info
in preparation
Languages

English

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