Characterization of the rat mesangial cell type 2 sulfonylurea receptor.

Author: AsanoK, CortesP, GarvinJ L, RiserB L, Rodríguez-BarberoA, SzamosfalviB, YeeJ

Paper Details 
Original Abstract of the Article :
Sulfonylurea receptors are classified as either high-affinity type 1 (SUR1) or low-affinity type 2 receptors (SUR2), and the gene expression of SURs has recently been demonstrated in kidney. However, functional data regarding a renal SUR are lacking. We previously demonstrated that mesangial cell (M...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/10354277

データ提供:米国国立医学図書館(NLM)

Characterization of the Rat Mesangial Cell Type 2 Sulfonylurea Receptor

The intricate workings of the human body, much like a vast desert, often conceal hidden pathways and mechanisms. This study focuses on sulfonylurea receptors, a type of protein crucial for regulating blood sugar. The researchers took a closer look at these receptors in rat mesangial cells, which are important for kidney function. This research used a combination of molecular biology techniques to investigate the presence and function of sulfonylurea receptors in rat mesangial cells. They found that these cells express a specific type of sulfonylurea receptor, suggesting a potential role in kidney function.

Understanding the Role of Sulfonylurea Receptors in Kidneys

The study's findings suggest a potential role for sulfonylurea receptors in regulating kidney function. This discovery could pave the way for new therapeutic targets for kidney diseases. Imagine finding a hidden spring in the desert - this study unveils a previously unknown aspect of kidney function.

Implications for Kidney Health and Beyond

The study's findings might have implications for understanding and treating kidney diseases. Further research is needed to elucidate the precise role of sulfonylurea receptors in kidney function and their potential as therapeutic targets. This discovery could be a stepping stone in developing new treatments for kidney diseases, offering a new oasis in the desert of kidney health.

Dr. Camel's Conclusion

This research sheds light on the previously unknown presence of sulfonylurea receptors in rat mesangial cells. It's like discovering a hidden oasis in a vast desert, offering new insights into kidney function. The findings could have significant implications for understanding and treating kidney diseases, potentially leading to the development of novel therapeutic strategies.

Date :
  1. Date Completed 1999-07-06
  2. Date Revised 2017-12-13
Further Info :

Pubmed ID

10354277

DOI: Digital Object Identifier

S0085-2538(15)46191-5

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English

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